Abstract Aims To investigate if Clostridium (Clostridioides) difficile infection (CDI),
traditionally thought of as hospital‐acquired, can be genomically linked to hospital or …

Although infections caused by Clostridioides difficile have historically been attributed to
hospital acquisition, growing evidence supports the role of community acquisition in C …

ObjectiveThis article describes a CDI outbreak in a long-term care (LTC) facility that used
molecular typing techniques and whole-genome sequencing to identify widespread …

Clostridioides difficile is the leading cause of healthcare-associated infectious diarrhoea.
However, it is increasingly appreciated that healthcare-associated infections derive from …

Background For over four decades, Clostridium difficile has been a significant enteric
pathogen of humans. It is associated with the use of antimicrobials that generally disrupt the …

Whole-genome sequencing (WGS) has yielded new insights into the transmission patterns
of healthcare facility-onset Clostridioides difficile infection (HO-CDI). WGS results prompted …

Abstract Background. Variation in Clostridium difficile infection (CDI) rates between
healthcare institutions suggests overall incidence could be reduced if the lowest rates could …

Background Estimates of the prevalence of asymptomatically carried Clostridium difficile in
elderly patients in long-term care range from 0% to 51%. Asymptomatic carriage is possibly …

Clostridioides difficile causes more healthcare-associated infections in the United States
than any other pathogen, with an estimated 500,000 infections and 29,000 deaths per year …

Clostridium difficile isolates from the environment are closely related to those from humans,
indicating a possible environmental transmission route for C. difficile infection (CDI). In this …