[HTML][HTML] Latent antibiotic resistance genes are abundant, diverse, and mobile in human, animal, and environmental microbiomes
Background Bacterial communities in humans, animals, and the external environment
maintain a large collection of antibiotic resistance genes (ARGs). However, few of these …
maintain a large collection of antibiotic resistance genes (ARGs). However, few of these …
Improved annotation of antibiotic resistance determinants reveals microbial resistomes cluster by ecology
Antibiotic resistance is a dire clinical problem with important ecological dimensions. While
antibiotic resistance in human pathogens continues to rise at alarming rates, the impact of …
antibiotic resistance in human pathogens continues to rise at alarming rates, the impact of …
[HTML][HTML] Mobile resistome of human gut and pathogen drives anthropogenic bloom of antibiotic resistance
Background The impact of human activities on the environmental resistome has been
documented in many studies, but there remains the controversial question of whether the …
documented in many studies, but there remains the controversial question of whether the …
[HTML][HTML] The structure and diversity of human, animal and environmental resistomes
Abstract Background Antibiotic resistance genes (ARGs) are widespread but cause
problems only when present in pathogens. Environments where selection and transmission …
problems only when present in pathogens. Environments where selection and transmission …
Metagenomic insight into the global dissemination of the antibiotic resistome
Q Zhang, N Xu, C Lei, B Chen, T Wang, Y Ma… - Advanced …, 2023 - Wiley Online Library
The global crisis in antimicrobial resistance continues to grow. Estimating the risks of
antibiotic resistance transmission across habitats is hindered by the lack of data on mobility …
antibiotic resistance transmission across habitats is hindered by the lack of data on mobility …
The antibiotic resistome: gene flow in environments, animals and human beings
The antibiotic resistance is natural in bacteria and predates the human use of antibiotics.
Numerous antibiotic resistance genes (ARGs) have been discovered to confer resistance to …
Numerous antibiotic resistance genes (ARGs) have been discovered to confer resistance to …
[HTML][HTML] Antibiotic resistome from the One-Health perspective: understanding and controlling antimicrobial resistance transmission
The concept of the antibiotic resistome was introduced just over a decade ago, and since
then, active resistome studies have been conducted. In the present study, we describe the …
then, active resistome studies have been conducted. In the present study, we describe the …
Context matters—the complex interplay between resistome genotypes and resistance phenotypes
G Dantas, MOA Sommer - Current opinion in microbiology, 2012 - Elsevier
Application of metagenomic functional selections to study antibiotic resistance genes is
revealing a highly diverse and complex network of genetic exchange between bacterial …
revealing a highly diverse and complex network of genetic exchange between bacterial …
[HTML][HTML] The antibiotic resistance “mobilome”: searching for the link between environment and clinic
JA Perry, GD Wright - Frontiers in microbiology, 2013 - frontiersin.org
Antibiotic resistance is an ancient problem, owing to the co-evolution of antibiotic-producing
and target organisms in the soil and other environments over millennia. The environmental …
and target organisms in the soil and other environments over millennia. The environmental …
[HTML][HTML] Antibiotic resistance genes in the environment: prioritizing risks
J Bengtsson-Palme, DG Larsson - Nature Reviews Microbiology, 2015 - nature.com
In a recent Opinion article (What is a resistance gene? Ranking risks in resistomes. Nature
Rev. Microbiol. 13, 116–123 (2015)) 1, Martínez et al. outline the obstacles associated with …
Rev. Microbiol. 13, 116–123 (2015)) 1, Martínez et al. outline the obstacles associated with …
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