[HTML][HTML] Molecular mechanisms of “antiphospholipid antibodies” and their paradoxical role in the pathogenesis of “seronegative APS”

R Misasi, A Longo, S Recalchi, D Caissutti… - International Journal of …, 2020 - mdpi.com
Antiphospholipid Syndrome (APS) is an autoimmune disease characterized by arterial
and/or venous thrombosis and/or pregnancy morbidity, associated with circulating …

[HTML][HTML] Mechanisms of endothelial dysfunction in antiphospholipid syndrome: association with clinical manifestations

M Velásquez, M Rojas, VM Abrahams… - Frontiers in …, 2018 - frontiersin.org
The endothelium is a monolayer of cells that covers the inner surface of blood vessels and
its integrity is essential for the maintenance of vascular health. Endothelial dysfunction is a …

[HTML][HTML] Obstetrical antiphospholipid syndrome: from the pathogenesis to the clinical and therapeutic implications

T Marchetti, M Cohen, P De Moerloose - Journal of Immunology …, 2013 - hindawi.com
Antiphospholipid syndrome (APS) is an acquired thrombophilia with clinical manifestations
associated with the presence of antiphospholipid antibodies (aPL) in patient plasma …

New insights in the pathophysiology of antiphospholipid syndrome

A Sacharidou, PW Shaul… - Seminars in thrombosis …, 2018 - thieme-connect.com
The antiphospholipid syndrome (APS) is an autoimmune disorder characterized by an
elevated risk for arterial and venous thrombosis and pregnancy-related morbidity. Since the …

Prothrombotic mechanisms based on the impairment of fibrinolysis in the antiphospholipid syndrome

R Forastiero, M Martinuzzo - Lupus, 2008 - journals.sagepub.com
Antiphospholipid syndrome (APS) is a clinical autoimmune disorder characterised by
thrombosis, venous or arterial, and recurrent pregnancy morbidity in association with the …

The role of complement in the antiphospholipid syndrome

JE Salmon, G Girardi - Current directions in autoimmunity, 2004 - books.google.com
The anti-phospholipid syndrome (APS) is characterized by recurrent fetal loss, vascular
thrombosis and thrombocytopenia occurring in the presence of antiphospholipid (aPL) …

Two-dimensional crystallization of annexin A5 on phospholipid bilayers and monolayers: a solid− solid phase transition between crystal forms

I Reviakine, W Bergsma-Schutter, AN Morozov… - Langmuir, 2001 - ACS Publications
Annexin A5 is a soluble protein which binds to negatively charged phospholipids, such as
dioleoylphosphatidylserine (DOPS), in the presence of Ca2+. A solid− solid phase transition …

Annexin-A5 and cell membrane repair

A Bouter, R Carmeille, C Gounou, F Bouvet… - Placenta, 2015 - Elsevier
Annexins are soluble proteins that bind to biological membranes containing negatively
charged phospholipids, principally phosphatidylserine, in a Ca 2+-dependent manner …

[HTML][HTML] E-Selectin mediates pathogenic effects of antiphospholipid antibodies

RG Espinola, X Liu, M Colden-Stanfield, J Hall… - Journal of Thrombosis …, 2003 - Elsevier
Antiphospholipid (aPL) antibodies, detected in patients with antiphospholipid syndrome
(APS) are associated with thrombosis, pregnancy loss and thrombocytopenia. Studies have …

[HTML][HTML] Antiphospholipid syndrome: complement activation, complement gene mutations, and therapeutic implications

S Chaturvedi, EM Braunstein, RA Brodsky - Journal of Thrombosis and …, 2021 - Elsevier
Antiphospholipid syndrome (APS) is an acquired thromboinflammatory disorder
characterized by the presence of antiphospholipid antibodies as well as an increased …