[HTML][HTML] A narrative review of positive regulation of NLRP3 inflammasome in rheumatoid arthritis

Y Zhuang, H Wang, J Su, J Zhang… - Annals of Palliative …, 2021 - apm.amegroups.org
Objective: This paper briefly reviews the pathological characteristics and regulatory
mechanism of NOD-like receptor family pyrin domain containing 3 (NLRP3) inflammasome …

[HTML][HTML] Role of NLRP3 inflammasome in rheumatoid arthritis

H Yin, N Liu, KR Sigdel, L Duan - Frontiers in Immunology, 2022 - frontiersin.org
Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by multi-articular,
symmetrical and invasive arthritis resulting from immune system abnormalities involving T …

[HTML][HTML] The NLRP3 Inflammasome as a Pathogenic Player Showing Therapeutic Potential in Rheumatoid Arthritis and Its Comorbidities: A Narrative Review

PK Chen, KT Tang, DY Chen - International Journal of Molecular …, 2024 - mdpi.com
Rheumatoid arthritis (RA) is an autoimmune inflammatory disease characterized by chronic
synovitis and the progressive destruction of cartilage and bone. RA is commonly …

[HTML][HTML] Role of the NLRP3 inflammasome in autoimmune diseases

Z Li, J Guo, L Bi - Biomedicine & pharmacotherapy, 2020 - Elsevier
NOD-like receptor family pyrin domain containing 3 (NLRP3) is an intracellular receptor that
senses foreign pathogens and endogenous danger signals. It assembles with apoptosis …

[HTML][HTML] NLRP3 inflammasome and its role in autoimmune diseases: A promising therapeutic target

W Ren, Y Sun, L Zhao, X Shi - Biomedicine & Pharmacotherapy, 2024 - Elsevier
The NOD-like receptor protein 3 (NLRP3) inflammasome is a protein complex that regulates
innate immune responses by activating caspase-1 and the inflammatory cytokines IL-1β and …

Therapeutic potential of targeting the NLRP3 inflammasome in rheumatoid arthritis

J Gao, H Zhang, Y Yang, J Tao - Inflammation, 2023 - Springer
NOD-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome is a
cytoplasmic multiprotein complex composed of the innate immune receptor protein NLRP3 …

The role of NLRP3 inflammasome in type 2 inflammation related diseases

S Xu, D Wang, L Tan, J Lu - Autoimmunity, 2024 - Taylor & Francis
Type 2 inflammation related diseases, such as atopic dermatitis, asthma, and allergic
rhinitis, are diverse and affect multiple systems in the human body. It is common for …

[HTML][HTML] The NLRP3 inflammasome: Contributions to inflammation-related diseases

Y Chen, X Ye, G Escames, W Lei, X Zhang, M Li… - Cellular & Molecular …, 2023 - Springer
The NOD-like receptor protein 3 (NLRP3) inflammasome is a protein complex that regulates
innate immune responses by activating caspase-1 and the inflammatory cytokines …

NLRP3 inflammasome activation contributes to the pathogenesis of rheumatoid arthritis

C Guo, R Fu, S Wang, Y Huang, X Li… - Clinical & …, 2018 - academic.oup.com
Nucleotide-binding, oligomerization domain (NOD)-like receptor family, pyrin domain
containing 3 (NLRP3) gene polymorphism was reported to be associated with susceptibility …

[HTML][HTML] Mechanistic and therapeutic insights into the function of NLRP3 inflammasome in sterile arthritis

Y Xiao, L Zhang - Frontiers in Immunology, 2023 - frontiersin.org
The NLRP3 inflammasome, which belongs to the pyrin domain containing 3 family of NOD-
like receptors, has a significant impact on both the innate and adaptive immune responses …