The evolutionary dynamics of the joint distribution of genotypes and phenotypes is studied.
The model, originally devised to study the joint effects of Mendelian and other types of …

Evolutionary models of continuous traits are developed. The models are based on the ideas
that:(1) the phenotype is the result of the interaction between genotype and environment;(2) …

A new approach for describing the evolution of polygenic traits subject to selection and
mutation is presented. Differential equations for the change of cumulants of the allelic …

The distributions of the mean phenotype and of the genetic variance of a polygenic trait
under a balance between mutation, stabilizing selection and genetic drift are investigated …

AN unequivocal demonstration of the extent of genetic variability in Mendelian populations
was recently carried out by HUBBY and LEWONTIN (1966; LE-WONTIN and HUBBY 1966) …

Conventional population genetics uses as primitive variables the frequencies and fitnesses
of individual genes. This paper develops a formalism whose primitive variables are the …

Equations for changes in the mean, variance and higher-order moments of a quantitative
trait are used to address the maintenance of heritable variation by mutation-selection …

In the 1st paper of this series [see ABA 44, 6010], a model was formulated for the evolution
of continuous variation. The present paper incorporates 2 modifications. Firstly, the …

I will argue that these problems are decoupled in prac-tice, because detailed genetic models
do not make useful predictions conceming the dynamics of the critical variance and …

The classical polygenic theory of inheritance postulates a large number of genes with small,
and essentially similar, effects. We propose instead a model with genes of gradually …