Recent discoveries involving the cytokine interleukin (IL)-6 have originated from diverse
disciplines, revealing roles in biological processes that are likewise varied. The most novel …

Abstract Interleukin-6 (IL-6) is a cytokine present in tumor microenvironment. Elevated level
of IL-6 is associated with cancer cell proliferation, angiogenesis and metastasis through …

Interleukin-7 (IL-7) is a multipotent cytokine that maintains the homeostasis of the immune
system. IL-7 plays a vital role in T-cell development, proliferation, and differentiation, as well …

Although IL-1β is the master inflammatory cytokine in the IL-1 family, after more than ten
years of continuous breeding, mice deficient in IL-1β exhibit no spontaneous disease …

The IL-6 family of cytokines consists of IL-6, IL-11, IL-27, IL-31, oncostatin M (OSM),
leukaemia inhibitory factor (LIF), ciliary neurotrophic factor (CNTF), cardiotrophin 1 (CT-1) …

Among inflammatory mediators, a growing body of evidence emphasizes the contribution of
the interleukin 17 (IL-17) cytokine family in malignant diseases. Besides IL-17A, the …

Cancer is a leading cause of death which imposes a substantial financial burden. Among
the several mechanisms involved in cancer progression, imbalance of immune cell‐derived …

Pro-inflammatory cytokines have been associated with chronic inflammation and
inflammatory diseases. Increased levels of interleukins (ILs) have been associated with …

Immune cytokines have been shown to play important roles in regulating immune cell
functions. Interleukin-4 (IL4), originally described as a B-cell growth factor, is known to …

Human cancer is characterized by deficits in antigen-specific immunity and intratumoral
CD8+ T cells. On the other hand, inflammatory macrophages and mediators of chronic …