Interleukin (IL)-6 is a pro-inflammatory cytokine that produces multifunctional effects.
Deregulated IL-6 production and signaling are associated with chronic inflammatory …

Objective Glioblastoma is the most frequent and malignant form of primary brain tumor with
grave prognosis. Mounting evidence supports that chronic inflammation (such as chronic …

The tumor microenvironment (TME) plays a major role in the pathogenesis of multiple
cancer types, including upper-gastrointestinal (GI) cancers that currently lack effective …

The authors report that significant titers of the proinflammatory cytokine interleukin‐1β (IL‐
1β) are present within the microenvironment of most breast carcinomas. A high IL‐1β …

Abstract Interleukin-17 (IL-17), a proinflammatory cytokine, mainly produced by Th17 cells,
participates in both innate and adaptive immune responses and is involved in various …

Abstract Interleukin-6 (IL-6) is a cytokine, which is involved in innate and acquired immunity,
in neural cell maintenance and in metabolism. IL-6 can be synthesized by many different …

Interleukin-7 (IL-7) is a non-hematopoietic cell-derived cytokine with a central role in the
adaptive immune system. It promotes lymphocyte development in the thymus and maintains …

Because of its immunosuppressive properties, interleukin-10 (IL-10) is thought to play an
important role in a number of human disease states, including inflammation, autoimmunity …

Interleukin-2 (IL-2) is a promising immunotherapeutic agent for the treatment of metastatic
melanoma, acute myelogenous leukemia, and metastatic renal cell carcinoma. While high …

Owing to its abundance in inflammatory settings, interleukin IL-6 is frequently viewed as a
proinflammatory cytokine, with functions that parallel those of tumor necrosis factor (TNF) …