Iron is an essential element for Escherichia, Salmonella, and Shigella species. The
acquisition of sufficient amounts of iron is difficult in many environments, including the …

Organisms generally respond to iron deficiency by increasing their capacity to take up iron
and by consuming intracellular iron stores. Escherichia coli, in which iron metabolism is …

Shigella spp. have transport systems for both ferric and ferrous iron. The iron can be taken
up as free iron or complexed to a variety of carriers. All Shigella species have both the Feo …

The importance of iron to bacteria is shown by the presence of numerous iron-scavenging
and transport systems and by many genes whose expression is tightly regulated by iron …

For most living organisms, iron is both essential and potentially toxic, making the precise
maintenance of iron homeostasis necessary for survival. To manage this paradox, bacteria …

The Fur protein is a primary regulator that monitors and controls cytoplasmic iron levels. We
now report the identification of a regulatory pathway mediated by the Salmonella response …

Iron is one of most abundant environmental metal ions but is highly limited in organisms. It is
an important metal ion as it facilitates various biological processes, including catalysis of …

Iron is a critical nutrient for the growth and survival of most bacterial species. Accordingly,
much attention has been paid to the mechanisms by which host organisms sequester iron …

Iron is an essential element but can be toxic at high concentrations. Therefore, its acquisition
and storage require tight control. Salmonella encodes the global regulator Fur (ferric uptake …

Iron, a major protein cofactor, is essential for most organisms. Despite the well-known effects
of O2 on the oxidation state and solubility of iron, the impact of O2 on cellular iron …