Presence of unfavorable cytogenetic abnormalities is the strongest predictor of poor survival in secondary myelofibrosis

D Dingli, SM Schwager, RA Mesa, CY Li… - … Journal of the …, 2006 - Wiley Online Library
Postpolycythemic and postthrombocythemic myeloid metaplasia are consensually referred
to as secondary myelofibrosis (sMF). Prognostic variables in sMF are not as well defined as …

Prognostic diversity among cytogenetic abnormalities in myelofibrosis with myeloid metaplasia

A Tefferi, D Dingli, CY Li, GW Dewald - Cancer, 2005 - Wiley Online Library
Abstract BACKGROUND Approximately 30–50% of patients with myelofibrosis with myeloid
metaplasia (MMM) demonstrate detectable cytogenetic abnormalities, the prognostic value …

Myelofibrosis with myeloid metaplasia: diagnosis, prognostic factors, and staging

F Cervantes, G Barosi - Seminars in oncology, 2005 - Elsevier
Myelofibrosis with myeloid metaplasia (MMM) is an infrequent disease usually affecting
elderly people. Due to the lack of a specific marker for MMM, efforts are being made to refine …

Prognostic factors and current practice in treatment of myelofibrosis with myeloid metaplasia: an update anno 2000

F Cervantes - Pathologie Biologie, 2001 - Elsevier
Median survival of patients with myelofibrosis with myeloid metaplasia (MMM) ranges from
3.5 to 5 years, but there is a wide variability. The degree of anemia (Hb< 10 g/dL) is the most …

Allogeneic hematopoietic stem cell transplant overcomes the adverse survival effect of very high risk and unfavorable karyotype in myelofibrosis

A Tefferi, DK Partain, JM Palmer… - American journal of …, 2018 - Wiley Online Library
The prognostic importance of genetic information in primary myelofibrosis (PMF) was
recently highlighted in a study of over 1000 cytogenetically‐annotated patients; 5‐year …

Myelofibrosis with myeloid metaplasia in young indidviduals: disease characteristics, prognostic factors and identification of risk groups

F Cervantes, G Barosi, JL Demory… - British journal of …, 1998 - Wiley Online Library
Myelofibrosis with myeloid metaplasia (MMM) is an uncommon disorder in young
individuals, for whom haemopoietic stem cell transplantation offers the only possibility of …

The role of cytogenetic abnormalities as a prognostic marker in primary myelofibrosis: applicability at the time of diagnosis and later during disease course

CS Tam, LV Abruzzo, KI Lin, J Cortes… - Blood, The Journal …, 2009 - ashpublications.org
Although cytogenetic abnormalities are important prognostic factors in myeloid
malignancies, they are not included in current prognostic scores for primary myelofibrosis …

Risk factors for leukemic transformation in patients with primary myelofibrosis

J Huang, CY Li, RA Mesa, W Wu… - … Journal of the …, 2008 - Wiley Online Library
BACKGROUND. Previous prognostic studies in primary myelofibrosis have focused on risk
factors for overall survival and have resulted in the establishment of several prognostic …

Myelofibrosis with myeloid metaplasia: diagnostic definition and prognostic classification for clinical studies and treatment guidelines

G Barosi - Journal of Clinical Oncology, 1999 - ascopubs.org
PURPOSE: Myelofibrosis with myeloid metaplasia (MMM) is a chronic myeloproliferative
disorder characterized by bone marrow fibrosis and extramedullary hematopoiesis. Recent …

Circulating hematopoietic progenitor cells predict survival in patients with myelofibrosis with myeloid metaplasia

V Sagaster, E Jager, A Weltermann… - …, 2003 - haematologica.org
BACKGROUND AND OBJECTIVES: The levels of circulating hematopoietic progenitor cells
are often increased in myelofibrosis with myeloid metaplasia (MMM). The prognostic …