The rise of CRISPR/Cas for genome editing in stem cells
B Shui, L Hernandez Matias, Y Guo… - Stem cells …, 2016 - Wiley Online Library
Genetic manipulation is a powerful tool to establish the causal relationship between a
genetic lesion and a particular pathological phenotype. The rise of CRISPR/Cas9 genome …
genetic lesion and a particular pathological phenotype. The rise of CRISPR/Cas9 genome …
[HTML][HTML] A broad overview and review of CRISPR-Cas technology and stem cells
SN Waddington, R Privolizzi, R Karda… - Current stem cell reports, 2016 - Springer
The pinnacle of four decades of research, induced pluripotent stem cells (iPSCs), and
genome editing with the advent of clustered, regularly interspaced, short palindromic …
genome editing with the advent of clustered, regularly interspaced, short palindromic …
CRISPR/Cas9‐mediated genome editing: From basic research to translational medicine
FV Jacinto, W Link, BI Ferreira - Journal of cellular and …, 2020 - Wiley Online Library
The recent development of the CRISPR/Cas9 system as an efficient and accessible
programmable genome‐editing tool has revolutionized basic science research …
programmable genome‐editing tool has revolutionized basic science research …
[HTML][HTML] A dual conditional CRISPR-Cas9 system to activate gene editing and reduce off-target effects in human stem cells
The CRISPR-Cas9 system has emerged as a powerful and efficient tool for genome editing.
An important drawback of the CRISPR-Cas9 system is the constitutive endonuclease activity …
An important drawback of the CRISPR-Cas9 system is the constitutive endonuclease activity …
[HTML][HTML] Advances in therapeutic CRISPR/Cas9 genome editing
N Savić, G Schwank - Translational Research, 2016 - Elsevier
Targeted nucleases are widely used as tools for genome editing. Two years ago the
clustered regularly interspaced short palindromic repeat (CRISPR)-associated Cas9 …
clustered regularly interspaced short palindromic repeat (CRISPR)-associated Cas9 …
Guidelines for optimized gene knockout using CRISPR/Cas9
CV Campenhout, P Cabochette, AC Veillard… - …, 2019 - Taylor & Francis
CRISPR/Cas9 technology has evolved as the most powerful approach to generate genetic
models both for fundamental and preclinical research. Despite its apparent simplicity, the …
models both for fundamental and preclinical research. Despite its apparent simplicity, the …
Progress and application of CRISPR/Cas technology in biological and biomedical investigation
J Lin, Y Zhou, J Liu, J Chen, W Chen… - Journal of Cellular …, 2017 - Wiley Online Library
Based on the tremendous progress of the understanding on the CRISPR‐Cas systems, the
application CRISPR/Cas technology has been extended into increasing scenarios in …
application CRISPR/Cas technology has been extended into increasing scenarios in …
[HTML][HTML] CRISPR/Cas9 genome-editing system in human stem cells: current status and future prospects
Z Zhang, Y Zhang, F Gao, S Han, KS Cheah… - … Therapy-Nucleic Acids, 2017 - cell.com
Genome-editing involves the insertion, deletion, or replacement of DNA in the genome of a
living organism using" molecular scissors." Traditional genome editing with engineered …
living organism using" molecular scissors." Traditional genome editing with engineered …
[HTML][HTML] CRISPR-mediated genome editing and human diseases
Abstract CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) technology
has emerged as a powerful technology for genome editing and is now widely used in basic …
has emerged as a powerful technology for genome editing and is now widely used in basic …
CRISPR/Cas9 genome editing: a promising tool for therapeutic applications of induced pluripotent stem cells
Y Zhang, D Sastre, F Wang - Current Stem Cell Research & …, 2018 - ingentaconnect.com
Background: Induced pluripotent stem cells hold tremendous potential for biological and
therapeutic applications. The development of efficient technologies for targeted genome …
therapeutic applications. The development of efficient technologies for targeted genome …
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