Go is a specific class (" other") of signal-transducing heterotrimeric GTP-binding proteins (G
proteins) that is expressed in high levels in mammalian brain. We have cloned two different …

Hybridization blot (Northern) analysis of mRNA coding for alpha subunits of the Go signal-
transducing protein detects three bands at 5.7, 4.2, and 3.2 kilobases (kb). We showed …

Glasgow, Glasgow, Scotland, and Department of Biochemistry, Rockefeller University, New
York, New York 10021 Received February 23, 1988; Revised Manuscript Received May 6 …

We determined the ontogeny of the GTP‐binding protein Go in rat brain and heart by
employing highly sensitive enzyme immunoassay methods. In the brain, the α subunit of Go …

The tissue and cellular distribution of a GTP‐binding protein, Go, was investigated in the rat
by immunochemical and immunohistochemical methods. Because the specific antibody for …

Four members of a family of GTP-binding proteins (G-proteins) which translate stimulation of
extracellular receptors into regulation of intracellular enzymes were isolated from the bovine …

Bovine brain contains two GTP-binding proteins, G and G0, which are substrates for ADP
ribosylation by pertussis toxin. The G protein mediates hormone and GTP inhibition of …

The ultrastructural localization of G o, a GTP-binding protein (G protein) highly expressed in
nervous tissues, was performed in cultured fetal and adult murine neurons, using affinity …

The alpha subunit of the guanine nucleotide-binding protein Go (" o" for other) is believed to
mediate signal transduction between a variety of receptors and effectors. cDNA clones …

Three closely related, but distinct, GTP-binding proteins (G-proteins) are encoded by cDNAs
arbitrarily designated Gi1, Gi2, and Gi3. The in vitro translated products of mRNAs prepared …