Background Cancer is the second most common cause of death. Oral squamous cell
carcinoma (OSCC) represents the most frequent of all oral neoplasms. Many treatment …

The potential of cinnamic acid as an anti-inflammatory and anti-cancer agent has been
studied previously. In our investigation, novel bio-isosters of cinnamyl sulfonamide …

Multiple genetic mutations along with unusual epigenetic modifications play a major role in
cancer development. Histone deacetylase (HDAC) enzyme overexpression observed in the …

Background: Although anticancer chemotherapeutics are available in markets, side effects
related to the drugs in clinical use lead to researchers to investigate new drug candidates …

Considering the therapeutic values of bioflavonoids in colon cancer treatment, six 2ʹ-
hydroxy chalcones (C1-C6) were synthesized, characterized and screened for in vitro …

Background Oral cancers although preventable, possess a low five-year survival rate which
has remained unchanged over the past three decades. In an attempt to find a more safe …

Oral cancer, as one of the most prevalent and invasive cancers that invade local tissue, can
cause metastasis, and have high mortality. In 2018, around 355,000 worldwide oral cancers …

Cancer has become the second main reason for worldwide disease-related deaths [1].
According to the key fact sheet of WHO (Accessed on May 1, 2019, https://www. who …

Background Biologic compounds have recently generated interest in cancer
chemoprevention. Sulforaphane (SFN), an isothiocyanate from cruciferous vegetables, has …

Oral squamous cell carcinoma (OSCC) is a global public health problem with high incidence
and mortality. The chemotherapeutic agents used in the clinic, alone or in combination …