Background and Purpose—The effect of pyrexia on cerebral ischemia has been extensively
studied in animals. In humans, however, such studies are small and the results conflicting …

Background and Purpose—Many studies associate fever with poor outcome in patients with
neurological injury, but this relationship is blurred by divergence in populations and …

Background and Purpose No definitive data are yet available on the effects of body
temperature on neurological damage after cerebral ischemia in humans. Experimental …

Prasad K, Krishnan PR. Fever is associated with doubling of odds of short‐term mortality in
ischemic stroke: an updated meta‐analysis. Acta Neurol Scand: 2010: 122: 404–408.© 2010 …

Background and Purpose—The association between hyperthermia and early neurological
deterioration, increased morbidity, and mortality in acute ischemic stroke is well known …

Background: Postischaemic pyrexia exacerbates neuronal damage. Hyperthermia related
cerebral changes have still not been well investigated in humans. Objective: To study how …

Background Hyperthermia is a frequent complication in patients with acute ischemic stroke.
On the other hand, therapeutically induced hypothermia has shown promising potential in …

Background and Purpose—Experimental studies have shown that hyperthermia is a
determinant of poor outcome after ischemic stroke. Clinical studies evaluating the effect of …

Previous studies showed that elevated body temperature early after ischemic stroke is
associated with severe neurological deficit and a poor outcome. The aim of this study was to …

Experimental evidence and clinical experience show that hypothermia protects the brain
from damage during ischaemia. There is a growing hope that the prevention of fever in …