“Insulin resistance” is a loosely defined term that implies a reduction below normal in the
ability of insulin to mediate one of its physiological functions. The term is usually applied in …

Context: Methods to directly measure insulin resistance are invasive, complex, and costly.
Surrogate indexes derived from the oral glucose tolerance test (OGTT) have been …

Insulin resistance contributes to the pathophysiology of diabetes and is a hallmark of
obesity, metabolic syndrome, and many cardiovascular diseases. Therefore, quantifying …

The objectives of this study were to evaluate test characteristics, such as normality of
distribution, variation, and repeatability, of simple fasting measures of insulin sensitivity and …

Insulin resistance is a hallmark of obesity, diabetes, and cardiovascular diseases, and leads
to many of the abnormalities associated with metabolic syndrome. Our understanding of …

Biological actions of insulin are essential for regulation and maintenance of glucose
homeostasis. Insulin resistance (typically defined as decreased sensitivity or …

AIM: This short review provides a theoretical outline for the measurement of insulin secretion
and insulin resistance in humans. DATA SYNTHESIS: To evaluate the ability to secrete …

Insulin resistance is a common condition, recognized to be a central feature of the metabolic
syndrome, and strongly associated with an increased risk of cardiovascular disease and …

The article discusses how to measure insulin resistance in muscle, liver, and adipose tissue
in human participants. The most frequently used methodologies to evaluate insulin …

Assessing insulin resistance in rodent models gives insight into mechanisms that cause type
2 diabetes and the metabolic syndrome. The hyperinsulinemic euglycemic glucose clamp …