[HTML][HTML] Blood and urine biomarkers in prostate cancer: Are we ready for reflex testing in men with an elevated prostate-specific antigen?

EK Chang, AJ Gadzinski, YA Nyame - Asian Journal of Urology, 2021 - Elsevier
Objective There is no consensus on the role of biomarkers in determining the utility of
prostate biopsy in men with elevated prostate-specific antigen (PSA). There are numerous …

Screening for prostate cancer—beyond total PSA, utilization of novel biomarkers

T Morgan, G Palapattu, J Wei - Current urology reports, 2015 - Springer
Urology has been beset by several major trends that have shifted the entire paradigm for
prostate cancer screening. These stem from a backlash against overdiagnosis and …

Improving the specificity of PSA screening with serum and urine markers

JT Kearns, DW Lin - Current urology reports, 2018 - Springer
Abstract Purpose of Review Prostate cancer remains a significant public health burden. In
order to decrease the morbidity and mortality associated with prostate cancer, serum …

Evaluation of blood and urine based biomarkers for detection of clinically-significant prostate cancer

HS Robinson, SS Lee, DA Barocas… - Prostate Cancer and …, 2024 - nature.com
Background Recognizing the limitations of prostate-specific antigen (PSA) screening and
the morbidity of prostate biopsies, several blood-and urine-based biomarkers have been …

[HTML][HTML] Beyond prostate specific antigen: new prostate cancer screening options

TA Narain, P Sooriakumaran - The world journal of men's health, 2022 - ncbi.nlm.nih.gov
Prostate specific antigen (PSA) is one of the best-known biomarkers for screening, diagnosis
and follow-up of patients for prostate cancer. Owing to several inherent limitations with PSA …

[HTML][HTML] Biomarkers for detection of clinically significant prostate cancer: contemporary clinical data and future directions

NW Eyrich, TM Morgan, JJ Tosoian - Translational Andrology and …, 2021 - ncbi.nlm.nih.gov
Use of serum prostate-specific antigen (PSA) testing for early detection of prostate cancer
appears to reduce cancer-specific mortality. Due to the limited specificity of PSA for clinically …

[HTML][HTML] Economic evaluation of urine-based or magnetic resonance imaging reflex tests in men with intermediate prostate-specific antigen levels in the United States

B Jiao, R Gulati, N Hendrix, JL Gore, S Rais-Bahrami… - Value in Health, 2021 - Elsevier
Objectives For men with intermediate prostate-specific antigen (PSA) levels (4-10 ng/mL),
urine-based biomarkers and multiparametric magnetic resonance imaging (MRI) are …

Serum markers in prostate cancer detection

O Bratt, H Lilja - Current opinion in urology, 2015 - journals.lww.com
Individualized, risk-adapted PSA testing intervals and reflex-testing of kallikrein-markers for
men with modestly increased PSA values may decrease the harms of screening. However …

Overdiagnosis and lives saved by reflex testing men with intermediate prostate-specific antigen levels

R Gulati, TM Morgan, T A'mar, SP Psutka… - JNCI: Journal of the …, 2020 - academic.oup.com
Abstract Background Several prostate cancer (PCa) early-detection biomarkers are
available for reflex testing in men with intermediate prostate-specific antigen (PSA) levels …

[HTML][HTML] Prostate cancer biomarkers: are we hitting the mark?

S McGrath, D Christidis, M Perera, SK Hong… - Prostate …, 2016 - Elsevier
Purpose Localised prostate cancer diagnosis and management is increasingly complex due
to its heterogeneous progression and prognostic subgroups. Pitfalls in current screening …