In this review, we discuss the available experimental evidences supporting the
chemopreventive efficacy of nonsteroidal anti-inflammatory drugs (NSAIDs) on colorectal …

Cyclooxygenase-2 (COX-2) is upregulated in a number of epithelial cancers, including in
upper aerodigestive tract (UADT) premalignant and malignant lesions. The purpose of this …

A large number of epidemiological studies have shown that regular use of aspirinor other
nonsteroidal anti-inflammatory drugs (NSAIDs) results in a 40–50% reduced risk of …

Summary Expression of cyclooxygenase 2 (COX-2) is believed to play an important role in
adenoma formation in murine polyposis models, and inhibition of COX-2 activity may, at …

Many epidemiological studies demonstrate that treatment with non-steroidal anti-
inflammatory drugs (NSAIDs) reduce the incidence and mortality of certain malignancies …

Cyclooxygenase 2 (COX-2) overexpression has been described in sporadic colonic
neoplasia, but its role in ulcerative colitis (UC) neoplastic progression remains unexplored …