Challenges of precision medicine for atherosclerotic cardiovascular disease based on human genome information

H Tada, S Usui, K Sakata, M Takamura… - … of Atherosclerosis and …, 2021 - jstage.jst.go.jp
Precision or personalized medicine is currently gaining a lot of attention. Clinical evidence
for its effectiveness has been established based on randomized clinical trials accounting for …

Clinical interpretation and management of genetic variants

AJ Marian - Basic to Translational Science, 2020 - jacc.org
Genetic variants are major determinants of susceptibility to disease, response to therapy,
and clinical outcomes. Advances in the short-read sequencing technologies, despite some …

Epigenetics and precision medicine in cardiovascular patients: from basic concepts to the clinical arena

S Costantino, P Libby, R Kishore, JC Tardif… - European heart …, 2018 - academic.oup.com
Cardiovascular diseases (CVDs) remain the leading cause of mortality worldwide and also
inflict major burdens on morbidity, quality of life, and societal costs. Considering that CVD …

New biomarker strategies to enable precision cardiovascular medicine

K Bede, WHW Tang - Current Opinion in Cardiology, 2018 - journals.lww.com
New biomarker strategies to enable precision cardiovascular... : Current Opinion in Cardiology
New biomarker strategies to enable precision cardiovascular medicine : Current Opinion in …

Prospects of personalized medicine in cardiovascular diseases

C Lenfant - Metabolism, 2013 - Elsevier
Cardiovascular diseases remain the dominant cause of death worldwide. In the last
decades, the remarkable advances in human genetic and genomic research, plus the now …

Screening for rare genetic variants associated with atherosclerosis: Opportunity for personalized medicine

A Peterlin, D Petrovič, B Peterlin - Current Vascular …, 2019 - ingentaconnect.com
Atherosclerosis and its clinical manifestations is a leading cause of disease burden
worldwide. Currently, most of the individuals carrying a strong predisposition to …

Genomic medicine in the prevention and treatment of atherosclerotic cardiovascular disease

S Tuteja, DJ Rader - Personalized Medicine, 2012 - Taylor & Francis
Cardiovascular disease (CVD) is the leading cause of death in the world. Over the past
decade considerable progress has been made in understanding the genomic basis of …

Cardiovascular precision medicine in the genomics era

AM Dainis, EA Ashley - JACC: Basic to Translational Science, 2018 - jacc.org
Precision medicine strives to delineate disease using multiple data sources—from genomics
to digital health metrics—in order to be more precise and accurate in our diagnoses …

[HTML][HTML] Genetics of cardiovascular disease: How far are we from personalized CVD risk prediction and management?

M Vrablik, D Dlouha, V Todorovova, D Stefler… - International journal of …, 2021 - mdpi.com
Despite the rapid progress in diagnosis and treatment of cardiovascular disease (CVD), this
disease remains a major cause of mortality and morbidity. Recent progress over the last two …

Current genomics in cardiovascular medicine

V Sawhney, S Brouilette, D Abrams… - Current …, 2012 - ingentaconnect.com
Cardiovascular disease (CVD) is a heterogeneous, complex trait that has a major impact on
human morbidity and mortality. Common genetic variation may predispose to common forms …