Abstract The Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/Cas
technology is a molecular tool specific to sequences for engineering genomes. Among …

The recent development of CRISPR–Cas systems as easily accessible and programmable
tools for genome editing and regulation is spurring a revolution in biology. Paired with the …

Despite the rapid application of next-generation sequencing (NGS) technologies, target
sequencing in regions of the genome is often required to diagnose many genetic diseases …

The recent introduction of clustered regularly interspaced short palindromic repeats
(CRISPR) and CRISPR associated protein (Cas) systems, offer an array of genome and …

Though the dust is still settling on the contentious CRISPR–Cas9 patent battle, the
conversation surrounding this revolutionary technology has only just begun. Since the …

CRISPR-Cas is a versatile genome editing technology that has been broadly applied in both
basic research and translation medicine. Ever since its discovery, the bacterial derived …

Cancer genomes commonly harbor many genetic aberrations which are often associated
with carcinogenesis, progression, metastasis and tolerance. The system of clustered …

Simple Summary It is widely believed that cancer is developed due to changes in the
genetic codes of our DNA, leading to abnormal growth of cells. In the past few years …

CRISPR-Cas9 technologies have transformed the study of genetic pathways governing
cellular differentiation and function. Recent advances have adapted these methods to …

Since its introduction to genome editing, CRISPR-Cas9 has been used to generate cell and
animal models of disease, investigate relations between genomes and phenotypes, and …