AtT-20 cells, which produce ß-endorphin, and AtT-20/hENK cells, which are AtT-20 cells
transfected with a proenkephalin gene, were implanted in the rat spinal subarachnoid space …

AtT-20 cells, which make and release beta-endorphin, or AtT-20/hENK cells, an AtT-20 cell
line transfected with the human proenkephalin gene and secreting enkephalin as well as …

The relief of neuropathic pain after spinal cord injury (SCI) remains daunting, because
pharmacologic intervention works incompletely and is accompanied by multiple side effects …

B16 F1C29 melanoma cells, which are thought to contain and release catecholamines, were
implanted in mouse and rat spinal subarachnoid space. B16 F1C29 cell implants …

Effective treatment of sensory neuropathies in peripheral neuropathies and spinal cord
injury (SCI) is one of the most difficult problems in modern clinical practice. Cell therapy to …

BACKGROUND Despite of numerous researches on the mechanisms and new therapeutic
methods of chronic pain, patients are still suffering even with the help of opioids. In recent …

Management of neuropathic pain remains problematic; however, cell therapy to treat the
effects of pain on the sensory system after spinal cord injury (SCI) could be a useful …

Chronic neuropathic pain is a common symptom in clinical practice and patients with chronic
pain are subject to a greatly impaired quality of life. Grafted genetically-modified cells …

The RN46A cell line was derived from embryonic day 13 rat medullary raphe cells by
infection with a retrovirus encoding the temperature-sensitive mutant of SV40 large T …

Adrenal chromaffin cells produce analgesic substances, such as catecholamines and
enkephalins, and intrathecal (it) implantation of either allografted adrenal tissue or …