Pemetrexed versus docetaxel in second line non-small-cell lung cancer: results and subsets analyses of a multi-center, randomized, exploratory trial in Chinese …

R Li, L Sun, J Wang, J Qian, Z Wang, X Jiao - Pulmonary pharmacology & …, 2012 - Elsevier
BACKGROUND: Pemetrexed and docetaxel are established therapies in second line non-
small cell lung cancer (NSCLC). Comparative data, concerning the two agents in the …

Safety analyses of pemetrexed-cisplatin and pemetrexed maintenance therapies in patients with advanced non-squamous NSCLC: Retrospective analyses from 2 …

CJ Langer, LG Paz-Ares, AJ Wozniak, C Gridelli… - Clinical Lung Cancer, 2017 - Elsevier
Background In a phase III study, maintenance pemetrexed showed superior survival over
placebo (PARAMOUNT) for patients with advanced non-squamous non-small cell lung …

[引用][C] PL-5 A phase III study of pemetrexed vs. docetaxel in patients with advanced non-small-cell lung cancer (NSCLC) who were previously treated with …

FA Shepherd, JR Pereira, J Von Pawel, U Gatzemeier… - Lung Cancer, 2003 - infona.pl
PL-5 A phase III study of pemetrexed vs. docetaxel in patients with advanced non-small-cell
lung cancer (NSCLC) who were previously treated with chemotherapy × Close The Infona …

Safety and effectiveness of pemetrexed in patients with non-small cell lung cancer in Japan-analysis of post-marketing surveillance

S Okubo, N Kobayashi, M Taketsuna… - Gan to Kagaku ryoho …, 2014 - europepmc.org
The safety and effectiveness of pemetrexed (PEM) in patients with non-small cell lung
cancer (NSCLC) were reviewed using data from post-marketing surveillance. Among 699 …

Pemetrexed monotherapy versus pemetrexed plus platinum combination as second-line treatment for advanced non-small cell lung cancer

Y Zhang, Z Chen, S Lu - Chinese medical journal, 2009 - mednexus.org
Background Pemetrexed is a novel folic acid antagonist with multiple targets, which has
been widely used in the treatment of non-small cell lung cancer (NSCLC). The objective of …

The role of pemetrexed as maintenance treatment in advanced NSCLC: a Phase III randomized trial: Evaluation of 'Maintenance pemetrexed plus best supportive care …

C Gridelli, M Di Maio - Expert Opinion on Pharmacotherapy, 2010 - Taylor & Francis
A randomized Phase III trial tested the efficacy of pemetrexed as maintenance treatment in
patients with advanced non-small-cell lung cancer (NSCLC) who were without progression …

Pemetrexed for heavily pretreated patients with advanced non-small cell lung cancer

JH Lee, CJ Yu, KY Chen, JY Shih, YL Lin… - Journal of the Formosan …, 2010 - Elsevier
BACKGROUND/PURPOSE: The efficacy and safety of chemotherapy as third-or higher-line
therapy for advanced non-small cell lung cancer (NSCLC) are unclear. The purpose of this …

A randomized phase II study of 500 mg/m2 and 1,000 mg/m2 of pemetrexed in patients (pts) with locally advanced or metastatic non-small cell lung cancer (NSCLC) …

Y Ichinose, K Nakagawa, T Tamura… - Journal of Clinical …, 2007 - ascopubs.org
7590 Background: Pemetrexed (Pem) 500 mg/m2 (Pem 500) is currently the standard
treatment for pts with locally advanced or metastatic NSCLC who had prior chemotherapy. In …

[HTML][HTML] Randomized phase II study of pemetrexed versus gefitinib in previously treated patients with advanced non-small cell lung cancer

YS Kim, EK Cho, HS Woo, J Hong… - … : Official Journal of …, 2016 - synapse.koreamed.org
Purpose This study aimed to evaluate the efficacy and safety of pemetrexed versus gefitinib
in patients with advanced non-small cell lung cancer (NSCLC) previously treated with …

Pemetrexed as second-line therapy for advanced non-small-cell lung cancer (NSCLC)

E Felip, R Rosell - Therapeutics and Clinical Risk Management, 2008 - Taylor & Francis
NSCLC accounts for 80% of all cases of lung cancer, which is the leading cause of cancer
mortality. The majority of NSCLC patients present with advanced, unresectable disease …