Relationships between chemical structure and activity of triterpenes against gram-positive and gram-negative bacteria

AG Pacheco, AFC Alcântara, VGC Abreu… - A Search for …, 2012 - books.google.com
Bacteria are non-chlorophyllated unicellular organisms that reproduce by fission and do not
present nuclear envelope. Grams stain is a staining technique used to classify bacteria …

[HTML][HTML] The synergistic effect of triterpenoids and flavonoids—New approaches for treating bacterial infections?

N Wrońska, M Szlaur, K Zawadzka, K Lisowska - Molecules, 2022 - mdpi.com
Currently, the pharmaceutical industry is well-developed, and a large number of
chemotherapeutics are being produced. These include antibacterial substances, which can …

[HTML][HTML] Synergistic antimicrobial activity between pentacyclic triterpenoids and antibiotics against Staphylococcus aureus strains

PY Chung, P Navaratnam, LY Chung - Annals of clinical microbiology and …, 2011 - Springer
Background There has been considerable effort to discover plant-derived antibacterials
against methicillin-resistant strains of Staphylococcus aureus (MRSA) which have …

In vitro effectiveness of triterpenoids and their synergistic effect with antibiotics against Staphylococcus aureus strains

M Hamza, M Nadir, N Mehmood… - Indian journal of …, 2016 - journals.lww.com
Objectives: The aim of this study is to evaluate the effect of four triterpenoids such as
oleanolic acid, ursolic acid, cycloastragenol, and beta-boswellic acid alone and in …

[HTML][HTML] Antimicrobial Potential of Natural and Semi-Synthetic ent-Kaurane and ent-Pimarane Diterpenes against Clinically Isolated Gram-Positive Multidrug …

ACF Soares, PM Matos, KF Silva… - Journal of the Brazilian …, 2019 - SciELO Brasil
In this work, a search for antimicrobial agents against multi-drug resistant (MDR) bacteria
was undertaken. It involved two natural diterpenes of different basic skeletons, named ent …

Pentacyclic triterpene derivatives possessing polyhydroxyl ring A inhibit Gram-positive bacteria growth by regulating metabolism and virulence genes expression

L Huang, H Luo, Q Li, D Wang, J Zhang, X Hao… - European Journal of …, 2015 - Elsevier
The hydroxyl group in ring A of pentacyclic triterpene is essential for antibacterial activity.
Pentacyclic triterpenes bearing three hydroxyl groups in ring A were mainly found in plants …

Pimarane‐type diterpenes obtained by biotransformation: antimicrobial properties against clinically isolated Gram‐positive multidrug‐resistant bacteria

TS Porto, MR Simão, LZ Carlos… - Phytotherapy …, 2013 - Wiley Online Library
The present study describes the antimicrobial activity of five pimarane‐type diterpenes
obtained by fungal biotransformation against several nosocomial multidrug‐resistant …

Bioactivity of Plant Constituents against Vancomycin-Resistant Enterococci

V Kuete - Fighting Multidrug Resistance with Herbal Extracts …, 2013 - Elsevier
The development of vancomycin resistance by some microbial strains has made the
treatment of some infections more difficult and, in many cases, impossible. Although the …

[HTML][HTML] Antimicrobial diterpenes: Recent development from natural sources

P Saha, FI Rahman, F Hussain… - Frontiers in …, 2022 - frontiersin.org
Antimicrobial resistance has been posing an alarming threat to the treatment of infectious
diseases over the years. Ineffectiveness of the currently available synthetic and …

Natural and hemi-synthetic pentacyclic triterpenes as antimicrobials and resistance modifying agents against Staphylococcus aureus: a review

L Catteau, L Zhu, F Van Bambeke… - Phytochemistry …, 2018 - Springer
Staphylococcus aureus infections are considered as seriously problematic for human health
and necessitate the development of new medicines and innovative antimicrobial strategies …