Fas Ligand-Mediated Lysis of Self Bystander Targets by Human Papillomavirus-Specific CD8+ Cytotoxic T Lymphocytes
MJ Smyth, E Krasovskis, RW Johnstone - Journal of virology, 1998 - Am Soc Microbiol
Mouse cytotoxic T lymphocytes (CTL) reactive with a H-2Db-presented 9-mer peptide of the
human papillomavirus type 16 protein E749-57 (RAHYNIVTF) were generated from the …
human papillomavirus type 16 protein E749-57 (RAHYNIVTF) were generated from the …
Delayed kinetics of tumor necrosis factor‐mediated bystander lysis by peptide‐specific CD8+ cytotoxic T lymphocytes
MJ Smyth, JD Sedgwick - European journal of immunology, 1998 - Wiley Online Library
Mouse CD8+ CTL reactive with an H‐2Db presented 9‐mer peptide of the human papilloma
virus 16 (HPV‐16) protein E749–57 (RAHYNIVTF) were generated from the splenocytes of …
virus 16 (HPV‐16) protein E749–57 (RAHYNIVTF) were generated from the splenocytes of …
Preferential utilization of the perforin/granzyme pathway for lysis of Epstein–Barr virus-transformed lymphoblastoid cells by virus-specific CD4+ T cells
A Khanolkar, H Yagita, MJ Cannon - Virology, 2001 - Elsevier
In this report, we show that Epstein–Barr virus (EBV)-infected lymphoblastoid cell lines (LCL)
express Fas and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) receptor 2 …
express Fas and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) receptor 2 …
Cytotoxic-T-lymphocyte human papillomavirus type 16 E5 peptide with CpG-oligodeoxynucleotide can eliminate tumor growth in C57BL/6 mice
YF Chen, CW Lin, YP Tsao, SL Chen - Journal of virology, 2004 - Am Soc Microbiol
Previously, we identified human papillomavirus type 16 (HPV-16) E5 as a tumor rejection
antigen that can induce cytotoxic T lymphocytes (CTLs) to protect against tumor growth (DW …
antigen that can induce cytotoxic T lymphocytes (CTLs) to protect against tumor growth (DW …
CD2/LFA‐3 or LFA‐l/ICAM‐1 but not CD28/B7 interactions can augment cytotoxicity by virus‐specific CD8+ cytotoxic T lymphocytes
R De Waal Malefyt, S Verma… - European journal of …, 1993 - Wiley Online Library
It is well established that adhesion molecules are required for interaction between cytotoxic
T lymphocytes (CTL) and target cells. Two adhesion pathways, CD2/LFA‐3 and LFA‐l/ICAM …
T lymphocytes (CTL) and target cells. Two adhesion pathways, CD2/LFA‐3 and LFA‐l/ICAM …
Human papillomavirus type 16 L1 capsomeres induce L1-specific cytotoxic T lymphocytes and tumor regression in C57BL/6 mice
P Ohlschlager, W Osen, K Dell, S Faath… - Journal of …, 2003 - Am Soc Microbiol
We analyzed capsomeres of human papillomavirus type 16 (HPV16) consisting of the L1
major structural protein for their ability to trigger a cytotoxic T-cell (CTL) response. To this …
major structural protein for their ability to trigger a cytotoxic T-cell (CTL) response. To this …
Expression of CD56 by human papillomavirus E7-specific CD8+ cytotoxic T lymphocytes correlates with increased intracellular perforin expression and enhanced …
AD Santin, PL Hermonat, A Ravaggi, S Bellone… - Clinical cancer …, 2001 - AACR
Human papillomavirus (HPV) infection represents the most important risk factor for
developing cervical cancer. In this study, we examine the potential of full-length E7-pulsed …
developing cervical cancer. In this study, we examine the potential of full-length E7-pulsed …
Cytotoxic T lymphocytes raised against a subdominant epitope offered as a synthetic peptide eradicate human papillomavirus type 16‐induced tumors
MCW Feltkamp, GR Vreugdenhil… - European journal of …, 1995 - Wiley Online Library
Previously, we have shown that immunization with human papillomavirus (HPV) type 16‐
derived cytotoxic T lymphocyte (CTL) epitope E7 49–57 (RAHYNIVTF) renders C57BL/6 …
derived cytotoxic T lymphocyte (CTL) epitope E7 49–57 (RAHYNIVTF) renders C57BL/6 …
Induction of specific CD8+ T-lymphocyte responses using a human papillomavirus-16 E6/E7 fusion protein and autologous dendritic cells
M Murakami, KJ Gurski, FM Marincola, J Ackland… - Cancer research, 1999 - AACR
When intracellular viral proteins are degraded, only a limited number of peptide epitopes are
capable of eliciting specific CD8+ cellular immune responses for a given human leukocyte …
capable of eliciting specific CD8+ cellular immune responses for a given human leukocyte …
Induction of human papilloma virus E6/E7-specific cytotoxic T-lymphocyte activity in immune-tolerant, E6/E7-transgenic mice
A Riezebos-Brilman, J Regts, EJ Freyschmidt, B Dontje… - Gene therapy, 2005 - nature.com
Despite promising preclinical results of various therapeutic anticancer immunization
strategies, these approaches may not be effective enough to eradicate tumors in cancer …
strategies, these approaches may not be effective enough to eradicate tumors in cancer …