Previous studies have shown that the precursor of olive oil secoiridoids, Oleuropein (OL)
has several in vitro chemopreventive properties. OL inhibits proliferation and induces …

Experimental and clinical findings suggest that olive oil has a protective effect, whereas oleic
acid consumption induces colorectal cancer (CRC). Considering this apparent contradiction …

Dietary quercetin (QU) and rutin (RU), phenolic flavonoids commonly found in many fruits
and vegetables, were provided to CF1 female mice for 50 weeks to assess the ability of …

Epidemiological evidence suggests that a diet abundant in fruits and vegetables may protect
against colon cancer. Bioactive compounds, including flavonoids and limonoids, have been …

Oleuropein, a non-toxic secoiridoid derived from the olive tree, is a powerful antioxidant and
anti-angiogenic agent. Here, we show it to be a potent anti-cancer compound, directly …

Purpose To assess the chemopreventive effect of oleanolic acid (ONA) and its synthetic
analog 18α-olean-12-ene-3β-23, 28-triol (OT) on azoxymethane (AOM)-induced colonic …

Background Azoxymethane (AOM) is a potent carcinogenic agent commonly used to induce
colon cancer in rats; the cytotoxicity of AOM is considered to mediate oxidative stress. This …

Epidemiological studies suggest that olive oil intake is associated to a reduced risk of
cancer. Recently, the chemopreventive activity of olive oil has been attributed to its unique …

BACKGROUND Animal model studies have shown that the colon tumour promoting effect of
dietary fat depends not only on the amount but on its fatty acid composition. With respect to …

Vitamin E, part of the body's primary lipid-soluble defense against free radicals and reactive
oxygen molecules, has been suggested to reduce the risk for some cancers. However, the …