Lower vitamin D levels and VDR FokI variants are associated with susceptibility to sepsis: a hospital-based case-control study

X Yang, J Ru, Z Li, X Jiang, C Fan - Biomarkers, 2022 - Taylor & Francis
Background: Vitamin D deficiency has been associated with increased sepsis incidence and
mortality in various populations. Vitamin D exerts its effect through vitamin receptor (VDR) …

Vitamin D receptor polymorphisms and vitamin D insufficiency are not associated with sepsis in critically ill children: a case-control study

I Shaheen, R Afifi, N Abulata, R Aboukhalil… - Egyptian Pediatric …, 2022 - Springer
Background Vitamin D is a fat-soluble vitamin that regulates calcium and phosphorous
homeostasis to maintain a healthy mineralized skeleton. It can also influence immune …

[HTML][HTML] Association of vitamin D receptor gene polymorphism with the risk of sepsis: A systematic review and meta-analysis

Q Li, W Li, M Chen, Y Chai, L Guan, Y Chen - Medicine, 2023 - journals.lww.com
Background: To investigate the association between sepsis and the vitamin D receptor
(VDR) gene polymorphisms. Methods: Databases including PubMed, Cochrane Library …

Vitamin D receptor gene polymorphisms association with the risk of sepsis and mortality

K Zeljic, A Elkilany, G Supic… - International journal …, 2017 - Wiley Online Library
Association of vitamin D receptor (VDR) gene polymorphisms with sepsis risk and mortality
was studied. VDR FokI CC genotype was associated with increased sepsis risk (OR …

Association between vitamin D receptor gene FokI polymorphism and mortality in patients with sepsis

SMK Bozgul, DA Emecen, FK Akarca, D Bozkurt… - Molecular Biology …, 2024 - Springer
Background Sepsis is life-threatening organ dysfunction as a result of the host's
dysregulated immune response to infection. The vitamin D receptor (VDR) gene FokI …

Association Between Vitamin D Status and Sepsis.

W Zhou, S Mao, L Wu, J Yu - Clinical laboratory, 2018 - search.ebscohost.com
Background: It is well-established that vitamin D status is closely associated with the
susceptibility to infections. We aimed to study the association between vitamin D status and …

Role and mechanism of vitamin D in sepsis

C Yang, Y Liu, W Wan - zhonghua wei zhong bing ji jiu yi xue, 2019 - europepmc.org
Objective Sepsis is a life-threatening organ dysfunction caused by the host's imbalance in
response to infection, which is still the leading cause of death in critically ill patients. In …

Serum vitamin D binding protein level, but not serum total, bioavailable, free vitamin D, is higher in 30-days survivors than in nonsurvivors with sepsis

JW Yoo, YK Jung, S Ju, SJ Lee, YJ Cho, YY Jeong… - Medicine, 2020 - journals.lww.com
The prognostic value of 3 types (total, bioavailable, and free) of 25-hydroxy vitamin D [25
(OH) D] and vitamin D binding protein (VDBP) in patients with sepsis is unknown. The aim of …

[HTML][HTML] Vitamin D-Binding Protein and the Role of its Gene Polymorphisms in the Mortality of Sepsis Patients

LA Kahar, Y Yusrawati, J Jamsari… - Acta Medica …, 2023 - ncbi.nlm.nih.gov
Objective. This study aimed to determine the role of vitamin D-binding protein (VDBP) gene
polymorphisms (especially at locus rs7041), vitamin D-binding protein levels, and vitamin D …

Genotyping of vitamin D receptor gene polymorphisms using mismatched amplification mutation assay in neonatal sepsis patients of Odisha, eastern India

B Das, S Patra, C Behera, M Suar - Infection, genetics and evolution, 2016 - Elsevier
Vitamin D has potent antimicrobial and anti-inflammatory properties. Vitamin D deficiency
has been shown to be associated with the risk of vulnerability to different infectious …