Asthma is characterized by chronic airway inflammation with intense eosinophil and
lymphocyte infiltration, mucus hyperproduction, and airway hyperresponsiveness …

Asthma is characterized by chronic airway inflammation with intense eosinophil and
lymphocyte infiltration, mucus hyperproduction, and airway hyperresponsiveness to a variety …

Highlights•Th17 cells and cytokines are associated with the more severe phenotypes of
asthma.•IL-17A and IL-17F are associated with increased neutrophils in the airway.•IL-17A …

Rationale: The IL-23–IL-17A–producing CD4+ T-cell (Th17 cell) axis plays an important role
in the development of chronic inflammatory diseases, including autoimmune diseases …

Asthma is the most prevalent allergic disease of the airway, which is characterized by
eosinophilic inflammation, mucus hyperproduction, and airway hyper-responsiveness …

Introduction: Asthma is a respiratory disorder typically characterized by T-helper type 2 (Th2)
inflammation that is mediated by cytokines, including IL-4, IL-5, and IL-13 …

Allergic rhinitis (AR) and chronic rhinosinusitis (CRS) are two widely prevalent inflammatory
diseases in the upper airways. T cell immunity has been suggested to play an important …

Steroid‐insensitive asthma is an infrequent but problematic airway disease that presents
with persistent symptoms, airflow limitation, or recurrent exacerbations even when treated …

BACKGROUND: IL-13 is a central mediator of airway responsiveness and mucus
expression in patients with allergic airway inflammation, and IL-13 is currently a therapeutic …

The Th2 cytokine IL-13 regulates several aspects of the asthmatic phenotype, including
airway inflammation, airway hyperresponsiveness, and mucus production. The Th17 …