LSF is a mammalian transcription factor that is rapidly and quantitatively phosphorylated
upon growth induction of resting, peripheral human T cells, as assayed by a reduction in its …

Terminally differentiated cells in Drosophila melanogaster wings and eyes are largely
resistant to proliferation upon deregulation of either E2F or cyclin E (CycE), but exogenous …

The cyclin-dependent kinase (CDK)–RB–E2F axis forms the core transcriptional machinery
driving cell cycle progression, dictating the timing and fidelity of genome replication and …

E2F8 is a transcriptional repressor that antagonizes E2F1 at the crossroads of the cell cycle,
apoptosis, and cancer. Previously, we discovered that E2F8 is a direct target of the APC/C …

The E2F family of transcription factors regulate the expression of many growth‐related
genes in a cell cycle‐dependent manner. These transcription factors can activate or, in …

The transcription factor E2F1 belongs to the E2F family and plays a crucial role during cell
cycle progression and apoptosis. Ser/Arg-Rich (SR) proteins are a family of RNA-binding …

E2F transcription factors are central regulators of cell division and cell fate decisions. E2F4
often represents the predominant E2F activity in cells. E2F4 is a transcriptional repressor …

The E2F family of transcription factors plays a central role in regulating cellular proliferation
by controlling the expression of both the genes required for cell cycle progression …

The E2F transcription factor, a heterodimer of E2F and DP subunits, is capable of driving the
G1–S transition of the cell cycle. However, mice in which the E2F-1 gene had been …

Unregulated expression of the transcription factor E2F promotes the G 1-to-S phase
transition in cultured mammalian cells. However, there has been no direct evidence for an …