[HTML][HTML] The unique immunomodulatory properties of MSC-derived exosomes in organ transplantation

Q Zheng, S Zhang, WZ Guo, XK Li - Frontiers in immunology, 2021 - frontiersin.org
Methods for suppressing the host immune system over the long term and improving
transplantation tolerance remain a primary issue in organ transplantation. Cell therapy is an …

Immunosuppressive effects of mesenchymal stem cells-derived exosomes

X Qian, N An, Y Ren, C Yang, X Zhang, L Li - Stem cell reviews and reports, 2021 - Springer
Mesenchymal stem cells (MSCs) have become important seed cells in therapy because of
their immunosuppressive function and anti-inflammatory effects. MSCs exert …

[HTML][HTML] Effects of mesenchymal stem cell-derived exosomes on autoimmune diseases

Z Shen, W Huang, J Liu, J Tian, S Wang… - Frontiers in …, 2021 - frontiersin.org
Recent years, the immunosuppressive properties of mesenchymal stem cells (MSCs) have
been demonstrated in preclinical studies and trials of inflammatory and autoimmune …

[HTML][HTML] Exosomes released from human bone marrow–derived mesenchymal stem cell attenuate acute graft-versus-host disease after allogeneic hematopoietic stem …

KL Li, JY Li, GL Xie, XY Ma - Frontiers in Cell and Developmental …, 2021 - frontiersin.org
Objective Mesenchymal stromal cell–derived exosomes have been applied for the treatment
of several immune diseases. This study aimed to explore the effect of human bone marrow …

[HTML][HTML] Mesenchymal stem cell-derived exosomes: a promising therapeutic ace card to address autoimmune diseases

H Baharlooi, M Azimi, Z Salehi… - International journal of …, 2020 - synapse.koreamed.org
With the development of novel treatments for autoimmune disorders, it has become a
popular research focus which mesenchymal stem cells (MSCs) have the capacity to …

Potential applications of mesenchymal stem cells and their derived exosomes in regenerative medicine

M Adelipour, DM Lubman, J Kim - Expert opinion on biological …, 2023 - Taylor & Francis
Introduction Regenerative medicine involves the replacement of damaged cells, tissues, or
organs to restore normal function. Mesenchymal stem cells (MSCs) and exosomes secreted …

[HTML][HTML] Immunomodulatory Potential of Human Adipose Mesenchymal Stem Cells Derived Exosomes on in vitro Stimulated T Cells

R Blazquez, FM Sanchez-Margallo… - Frontiers in …, 2014 - frontiersin.org
In the recent years, it has been demonstrated that the biological activity of mesenchymal
stem cells (MSCs) is mediated through the release of paracrine factors. Many of these …

[HTML][HTML] Mesenchymal stromal/stem cell (MSC)-derived exosomes in clinical trials

A Lotfy, NM AboQuella, H Wang - Stem Cell Research & Therapy, 2023 - Springer
Mesenchymal stromal/stem cells (MSCs) are widely utilized in cell therapy because of their
robust immunomodulatory and regenerative properties. Their paracrine activity is one of the …

[HTML][HTML] Therapeutic features and updated clinical trials of mesenchymal stem cell (MSC)-derived exosomes

BC Lee, I Kang, KR Yu - Journal of clinical medicine, 2021 - mdpi.com
Identification of the immunomodulatory and regenerative properties of mesenchymal stem
cells (MSCs) have made them an attractive alternative therapeutic option for diseases with …

[HTML][HTML] Mesenchymal stem cell-derived exosomes and other extracellular vesicles as new remedies in the therapy of inflammatory diseases

CR Harrell, N Jovicic, V Djonov, N Arsenijevic… - Cells, 2019 - mdpi.com
There is growing evidence that mesenchymal stem cell (MSC)-based immunosuppression
was mainly attributed to the effects of MSC-derived extracellular vesicles (MSC-EVs). MSC …