The cellular and molecular genetic aberrations of hematopoietic and lymphoid tissues are
increasingly important in leukemia classification and are prognostically significant. Although …

The complex variants of t (8; 21) involving chromosomes 8 and 21 as well as a variable
chromosome account for 1.1∼ 5% of acute myeloid leukemia (AML) patients. This paper …

Translocation t (7; 11)(p15; p15) is an uncommon but recurrent chromosome aberration in
acute myeloid leukaemia (AML), which occurs mostly in oriental patients and in AML M2 or …

Abstract The t (8; 21)(q22; q22) is the most common translocation in acute myeloid leukemia
(AML). We describe the clinicopathologic and cytogenetic profile of 117 patients with t (8; 21) …

The translocation t (8; 21)(q22; q22) frequently associated with additional chromosomal
aberrations is one of the most recurrent chromosomal abnormalities in AML. Clinically, this …

A complex three-way t (8; 18; 16)(p11; q21; p13) was detected in a 15-month-old patient with
acute myeloid leukemia (AML). The patient had typical clinical manifestation and bone …

“Simple” variants of the t (8; 21) translocation involving chromosome 8 and a chromosome
other than number 21 are rare. To our knowledge, only t (3; 8)(q29; q22), t (8; 11)(q22; q13) …

The t (8; 21) abnormality occurs in a minority of acute myeloid leukemia (AML) patients. The
translocation results in an in‐frame fusion of two genes, resulting in a fusion protein of one N …

Abstract The translocation (8; 21)(q22; q22) is commonly associated with acute myeloid
leukemia (AML) M2 according to the French‐American‐British (FAB) classification. We …

Background Acute myeloid leukemia (AML) is a complex hematological disease
characterized by genetic and clinical heterogeneity. The identification and understanding of …