INTRODUCTION Under homeostasis, the central nervous system (CNS) hosts microglia
(MG) and CNS-associated macrophages (CAMs). During experimental autoimmune …

Astrocytes are the most abundant cell type in the brain, where they perform a wide array of
functions, yet the nature of their cellular heterogeneity and how it oversees these diverse …

INTRODUCTION Glial cells of the central nervous system (CNS), including astrocytes and
microglia, play critical roles in development, tissue repair, and homeostasis. However …

Single-cell transcriptomics (scRNA-seq) has greatly advanced our ability to characterize
cellular heterogeneity. However, scRNA-seq requires lysing cells, which impedes further …

Synapses are crucial structures that mediate signal transmission between neurons in
complex neural circuits and display considerable morphological and electrophysiological …

Transcriptome profiling is widely used to infer functional states of specific cell types, as well
as their responses to stimuli, to define contributions to physiology and pathophysiology …

Microglia are macrophages present in the brain that function as the primary and most
important source of immune response in the central nervous system (CNS). Regardless of …

Astrocytes are heterogeneous glial cells of the central nervous system,–. However, the
physiological relevance of astrocyte diversity for neural circuits and behaviour remains …

Reactive astrogliosis is a reaction of astrocytes to disturbed homeostasis in the central
nervous system (CNS), accompanied by changes in astrocyte numbers, morphology, and …

Astrocytes and microglia are non-neuronal cells that maintain homeostasis within the central
nervous system via their capacity to regulate neuronal transmission and prune synapses …