Epigenetics in health and disease

L Zhang, Q Lu, C Chang - Epigenetics in allergy and autoimmunity, 2020 - Springer
Epigenetic mechanisms, which include DNA methylation, histone modification, and
microRNA (miRNA), can produce heritable phenotypic changes without a change in DNA …

Epigenetics and autoimmune diseases

P Quintero-Ronderos, G Montoya-Ortiz - Autoimmune diseases, 2012 - Wiley Online Library
Epigenetics is defined as the study of all inheritable and potentially reversible changes in
genome function that do not alter the nucleotide sequence within the DNA. Epigenetic …

Epigenetic mechanisms in the context of complex diseases

J Van Vliet, NA Oates, E Whitelaw - Cellular and molecular life sciences, 2007 - Springer
Complex diseases arise from a combination of heritable and environmental factors. The
contribution made by environmental factors may be mediated through epigenetics …

Epigenetics: the link between nature and nurture

SA Tammen, S Friso, SW Choi - Molecular aspects of medicine, 2013 - Elsevier
While the eukaryotic genome is the same throughout all somatic cells in an organism, there
are specific structures and functions that discern one type of cell from another. These …

Epigenomes as therapeutic targets

CA Hamm, FF Costa - Pharmacology & Therapeutics, 2015 - Elsevier
Epigenetics is a molecular phenomenon that pertains to heritable changes in gene
expression that do not involve changes in the DNA sequence. Epigenetic modifications in a …

Epigenetics and human disease: translating basic biology into clinical applications

D Rodenhiser, M Mann - Cmaj, 2006 - Can Med Assoc
Epigenetics refers to the study of heritable changes in gene expression that occur without a
change in DNA sequence. Research has shown that epigenetic mechanisms provide an" …

The key role of epigenetics in human disease prevention and mitigation

AP Feinberg - New England Journal of Medicine, 2018 - Mass Medical Soc
Epigenetics in Disease Prevention and Mitigation Epigenetics is the regulation of gene
expression through alterations in DNA or associated factors (other than the DNA sequence) …

[HTML][HTML] How epigenetics impacts on human diseases

A Farsetti, B Illi, C Gaetano - European journal of internal medicine, 2023 - Elsevier
Epigenetics is a rapidly growing field of biology that studies the changes in gene expression
that are not due to alterations in the DNA sequence but rather the chemical modifications of …

[PDF][PDF] Epigenetic studies in human diseases

J Halušková - Folia Biol (Praha), 2010 - fb.cuni.cz
Irreversible genetic alterations underlying human diseases have been widely studied to
date. However, it is evident that the potentially reversible epigenetic dysregulations may also …

Epigenetics: molecular mechanisms and implications for disease

AE Handel, GC Ebers, SV Ramagopalan - Trends in molecular medicine, 2010 - cell.com
Epigenetics is rising to prominence in biology as a mechanism by which environmental
factors have intermediate-term effects on gene expression without changing the underlying …