Heartburn is the most specific symptom of gastroesophageal reflux disease (GERD). In
clinical practice, heartburn relief by a proton pump inhibitor (PPI) trial does suffice to confirm …

Background & Aims Analyses of impedance parameters such as the post-reflux swallow-
induced peristaltic wave (PSPW) index and the mean nocturnal baseline impedance (MNBI) …

The clinical diagnosis of gastro-esophageal reflux disease (GERD) is based on the
presence of typical esophageal troublesome symptoms. In clinical practice, heartburn relief …

Background On‐therapy impedance‐pH monitoring in proton pump inhibitor (PPI)‐refractory
gastroesophageal reflux disease (GERD) yielded conflicting results. We aimed to assess the …

Background By analysis of symptom‐reflux association, endoscopy‐negative refractory
heartburn can be related to acid/non‐acid refluxes with impedance‐pH monitoring …

Summary Background The Lyon Consensus delineates impedance‐pH parameters that can
demonstrate/exclude gastro‐oesophageal reflux disease (GERD). In patients with acid …

Gastro-oesophageal reflux disease (GERD) is a highly prevalent condition in Western
countries leading to millions of outpatient visits per year. GERD symptoms including …

INTRODUCTION: Functional heartburn is defined by Rome III criteria as an endoscopy-
negative condition with normal oesophageal acid exposure time, negative symptom …

Background A hierarchical approach for gastro‐oesophageal reflux disease (GERD)
diagnosis by impedance‐pH monitoring was proposed by the Lyon Consensus, based on …

Gastroesophagel reflux disease (GERD) is a common condition encountered in clinical
practice. Over the years there has been a continuous interaction between the understanding …