Cell type classification and unsupervised morphological phenotyping from low-resolution images using deep learning

K Yao, ND Rochman, SX Sun - Scientific reports, 2019 - nature.com
Convolutional neural networks (ConvNets) have proven to be successful in both the
classification and semantic segmentation of cell images. Here we establish a method for cell …

From quantitative microscopy to automated image understanding

K Huang, RF Murphy - Journal of biomedical optics, 2004 - spiedigitallibrary.org
Quantitative microscopy has been extensively used in biomedical research and has
provided significant insights into structure and dynamics at the cell and tissue level. The …

[HTML][HTML] Novel genotype-phenotype associations in human cancers enabled by advanced molecular platforms and computational analysis of whole slide images

LAD Cooper, J Kong, DA Gutman, WD Dunn… - Laboratory …, 2015 - Elsevier
Technological advances in computing, imaging, and genomics have created new
opportunities for exploring relationships between histology, molecular events, and clinical …

Applications in image-based profiling of perturbations

JC Caicedo, S Singh, AE Carpenter - Current opinion in biotechnology, 2016 - Elsevier
Highlights•Image-based profiling uses hundreds of measurements of cell morphology from
images.•Samples with similar phenotypes are grouped based on this unbiased, quantitative …

CellProfiler Analyst: interactive data exploration, analysis and classification of large biological image sets

D Dao, AN Fraser, J Hung, V Ljosa, S Singh… - …, 2016 - academic.oup.com
CellProfiler Analyst allows the exploration and visualization of image-based data, together
with the classification of complex biological phenotypes, via an interactive user interface …

Pattern recognition software and techniques for biological image analysis

L Shamir, JD Delaney, N Orlov, DM Eckley… - PLoS computational …, 2010 - journals.plos.org
The increasing prevalence of automated image acquisition systems is enabling new types of
microscopy experiments that generate large image datasets. However, there is a perceived …

CellProfiler Analyst 3.0: accessible data exploration and machine learning for image analysis

DR Stirling, AE Carpenter, BA Cimini - Bioinformatics, 2021 - academic.oup.com
Image-based experiments can yield many thousands of individual measurements describing
each object of interest, such as cells in microscopy screens. CellProfiler Analyst is a free …

CellProfiler: image analysis software for identifying and quantifying cell phenotypes

AE Carpenter, TR Jones, MR Lamprecht, C Clarke… - Genome biology, 2006 - Springer
Biologists can now prepare and image thousands of samples per day using automation,
enabling chemical screens and functional genomics (for example, using RNA interference) …

High throughput microscopy: from raw images to discoveries

R Wollman, N Stuurman - Journal of cell science, 2007 - journals.biologists.com
Technological advances in automated microscopy now allow rapid acquisition of many
images without human intervention, images that can be used for large-scale screens. The …

CP-CHARM: segmentation-free image classification made accessible

V Uhlmann, S Singh, AE Carpenter - BMC bioinformatics, 2016 - Springer
Background Automated classification using machine learning often relies on features
derived from segmenting individual objects, which can be difficult to automate. WND …