[HTML][HTML] Proinflammatory cytokine gene polymorphisms in bullous pemphigoid

PS Tabatabaei-Panah, H Moravvej, Z Sadaf… - Frontiers in …, 2019 - frontiersin.org
Bullous pemphigoid (BP) is a rare autoimmune skin blistering disease, characterized by the
presence of autoantibodies against hemidesmosomal autoantigens. Cytokine expression is …

[HTML][HTML] Circulating eosinophil and neutrophil counts correlate with disease severity in bullous pemphigoid

SH Park, SH Lee, JH Kim, SC Kim - Annals of Dermatology, 2018 - ncbi.nlm.nih.gov
Background Bullous pemphigoid (BP) is an autoimmune subepidermal blistering disease
characterized by tissue-bound and circulating autoantibodies directed against BP180 and/or …

[HTML][HTML] NET formation in bullous pemphigoid patients with relapse is modulated by IL-17 and IL-23 interplay

D Giusti, E Bini, C Terryn, K Didier, S Le Jan… - Frontiers in …, 2019 - frontiersin.org
Background: DNA extracellular traps (ETs), released by neutrophils (NETs), or eosinophils
(EETs), play a pathogenic role in several autoimmune disorders. However, to date, NETs …

Immunological features and factors associated with mucocutaneous bullous pemphigoid–a retrospective cohort study

S Ständer, E Schmidt, D Zillikens… - JDDG: Journal der …, 2021 - Wiley Online Library
Background and objectives The features of bullous pemphigoid (BP) patients presenting
with mucosal lesions are not established. We aimed to elucidate the clinical and …

Clinical course and outcomes of pemphigus vulgaris and foliaceus: A retrospective study using a nationwide database in Japan

H Miyachi, T Konishi, Y Hashimoto… - The Journal of …, 2023 - Wiley Online Library
Pemphigus is a life‐threatening autoimmune blistering disease. Patient characteristics,
treatment courses, and outcomes remain unclear owing to its rarity. To describe the …

[HTML][HTML] The role of eosinophils in bullous pemphigoid: a developing model of eosinophil pathogenicity in mucocutaneous disease

KT Amber, M Valdebran, K Kridin, SA Grando - Frontiers in Medicine, 2018 - frontiersin.org
Bullous pemphigoid (BP) is an autoimmune blistering disease which carries a significant
mortality and morbidity. While historically BP has been characterized as an IgG driven …

Emerging treatments for pemphigoid diseases

RJ Ludwig, K Kalies, J Köhl, D Zillikens… - Trends in molecular …, 2013 - cell.com
Incidence of bullous pemphigoid (BP), the main pemphigoid disease, has increased over
the past decades. Despite growing insights into pathogenic mechanisms, treatment is still …

Mechanism‐based therapeutic targets of pemphigus vulgaris: A scoping review of pathogenic molecular pathways

B Kaur, J Kerbrat, J Kho, M Kaler… - Experimental …, 2022 - Wiley Online Library
Pemphigus vulgaris (PV) is a potentially fatal autoimmune blistering disease characterised
by cell‐cell detachment or acantholysis. The mechanisms which follow antibody (Ab) …

Cytokine pattern in blister fluid and sera of patients with pemphigus

A Baroni, B Perfetto, E Ruocco, R Greco, D Criscuolo… - Dermatology, 2002 - karger.com
Background: Pemphigus is a chronic auto-immune blistering disease with four main
variants, ie pemphigus vulgaris (PV), foliaceus (PF), erythematosus (PE) and vegetans. The …

[HTML][HTML] The intersection of IgE autoantibodies and eosinophilia in the pathogenesis of bullous pemphigoid

KN Messingham, TP Crowe, JA Fairley - Frontiers in immunology, 2019 - frontiersin.org
Bullous pemphigoid (BP) is an autoimmune blistering disease characterized by
autoantibodies targeting cellular adhesion molecules. While IgE autoantibodies are …