It is commonly assumed that the only goal of anticancer chemotherapy, like antimicrobial
antibiotic therapy, is to eradicate by direct cytotoxic effects all tumor cells. According to this …

In contrast to prior belief, tumor cell apoptosis is not necessarily silent but can be
immunogenic. By tracing how anthracyclines and γ-irradiation trigger immunogenic cell …

Dying tumour cells can elicit a potent anticancer immune response by exposing the
calreticulin (CRT)/ERp57 complex on the cell surface before the cells manifest any signs of …

In response to some chemotherapeutic agents such as anthracyclines and oxaliplatin,
cancer cells undergo immunogenic apoptosis, meaning that their corpses are engulfed by …

Calreticulin exposure increases cancer immunogenicity | Nature Biotechnology Skip to
main content Thank you for visiting nature.com. You are using a browser version with …

The treatment of cancer by chemotherapy causes tumour cell death, mostly by apoptosis.
This tumour cell death may or may not elicit an immune response. At least in some cases …

The conventional treatment of cancer relies upon radiotherapy and chemotherapy. Such
treatments supposedly mediate their effects via the direct elimination of tumor cells …

Experiments performed in mice revealed that anthracyclines stimulate immunogenic cell
death that is characterized by the pre-apoptotic exposure of calreticulin (CRT) on the surface …

Some chemotherapeutic agents can elicit apoptotic cancer cell death, thereby activating an
anticancer immune response that influences therapeutic outcome. We previously reported …

Anthracyclin-treated tumor cells are particularly effective in eliciting an anticancer immune
response, whereas other DNA-damaging agents such as etoposide and mitomycin C do not …