Systemic delivery of curcumin: 21st century solutions for an ancient conundrum

S Bisht, A Maitra - Current drug discovery technologies, 2009 - ingentaconnect.com
Curcumin, a polyphenolic compound derived from the dietary spice turmeric, possesses
diverse pharmacologic effects including anti-inflammatory, anti-oxidant, anti-proliferative and …

Novel curcumin oral delivery systems

T Kurita, Y Makino - Anticancer research, 2013 - ar.iiarjournals.org
Curcumin, a natural polyphenolic compound derived from turmeric (Curcuma longa L), has
proven to be a modulator of multiple intercellular signalling pathways linked to inflammation …

Conundrum and therapeutic potential of curcumin in drug delivery

A Kumar, A Ahuja, J Ali… - Critical Reviews™ in …, 2010 - dl.begellhouse.com
Turmeric, the source of the polyphenolic active compound curcumin (diferuloylmethane),
has been used extensively in traditional medicine since ancient times as a household …

Bioavailability of curcumin: problems and promises

P Anand, AB Kunnumakkara, RA Newman… - Molecular …, 2007 - ACS Publications
Curcumin, a polyphenolic compound derived from dietary spice turmeric, possesses diverse
pharmacologic effects including anti-inflammatory, antioxidant, antiproliferative and …

[HTML][HTML] Improving curcumin bioavailability: Current strategies and future perspectives

R Tabanelli, S Brogi, V Calderone - Pharmaceutics, 2021 - mdpi.com
Curcumin possesses a plethora of interesting pharmacological effects. Unfortunately, it is
also characterized by problematic drug delivery and scarce bioavailability, representing the …

[HTML][HTML] Biomedical applications and bioavailability of curcumin—An updated overview

SI Sohn, A Priya, B Balasubramaniam… - Pharmaceutics, 2021 - mdpi.com
Curcumin, a yellow-colored molecule derived from the rhizome of Curcuma longa, has been
identified as the bioactive compound responsible for numerous pharmacological activities of …

Pharmacological and clinical properties of curcumin

CS Beevers, S Huang - Botanics: Targets and Therapy, 2011 - Taylor & Francis
The polyphenol natural product curcumin has been the subject of numerous studies over the
past decades, which have identified and characterized the compound's pharmacokinetic …

An update on the pharmacological usage of curcumin: has it failed in the drug discovery pipeline?

F Olotu, C Agoni, O Soremekun… - Cell Biochemistry and …, 2020 - Springer
The pharmacological propensities of curcumin have been reported in a plethora of pre-
clinical and clinical studies. However, innate attributes account for extremely low oral …

[HTML][HTML] Curcumin―the paradigm of a multi-target natural compound with applications in cancer prevention and treatment

MH Teiten, S Eifes, M Dicato, M Diederich - Toxins, 2010 - mdpi.com
As cancer is a multifactor disease, it may require treatment with compounds able to target
multiple intracellular components. We summarize here how curcumin is able to modulate …

Curcumin as a clinically-promising anti-cancer agent: pharmacokinetics and drug interactions

J Adiwidjaja, AJ McLachlan… - Expert opinion on drug …, 2017 - Taylor & Francis
Introduction: Curcumin has been extensively studied for its anti-cancer properties. While a
diverse array of in vitro and preclinical research support the prospect of curcumin use as an …