Effectiveness and safety of rivaroxaban versus warfarin in obese patients with acute venous thromboembolism: analysis of electronic health record data

OS Costa, J Beyer-Westendorf, V Ashton… - Journal of Thrombosis …, 2021 - Springer
There is limited data evaluating clinical outcomes of rivaroxaban versus warfarin in obese
patients with venous thromboembolism (VTE). Our objective was to evaluate the …

[HTML][HTML] Rivaroxaban versus warfarin treatment among morbidly obese patients with venous thromboembolism: comparative effectiveness, safety, and costs

AC Spyropoulos, V Ashton, YW Chen, B Wu… - Thrombosis research, 2019 - Elsevier
Introduction Limited data exist on direct-acting oral anticoagulants in morbidly obese
patients with venous thromboembolism (VTE). We compared clinical and health/economic …

Management of venous thromboembolism in morbid obesity with rivaroxaban or warfarin

P Weaver, TH Ng, T Breeden… - Annals of …, 2022 - journals.sagepub.com
Background Rivaroxaban is a first-line option for the management of venous
thromboembolism (VTE). However, limited data are available regarding its effectiveness in …

Effectiveness, safety, and healthcare costs associated with rivaroxaban versus warfarin among venous thromboembolism patients with obesity: a real-world study in …

JS Berger, F Laliberté, A Kharat, D Lejeune… - Journal of Thrombosis …, 2022 - Springer
Prior observational studies suggest rivaroxaban is safe and effective among patients with
morbid obesity who suffered a venous thromboembolism (VTE) event, but existing data are …

Treatment of venous thromboembolism with rivaroxaban in relation to body weight

M Di Nisio, MC Vedovati, A Riera-Mestre… - Thrombosis and …, 2016 - thieme-connect.com
The pharmacokinetics of oral rivaroxaban are highly predictable and only affected to a
limited extent by bodyweight; therefore, dose adjustments for bodyweight are not required …

Apixaban and rivaroxaban in obese patients treated for venous thromboembolism: drug levels and clinical outcomes

A Ballerie, RN Van, K Lacut, H Galinat, C Rousseau… - Thrombosis research, 2021 - Elsevier
Background Direct oral anticoagulants (DOAC) use remains challenging in obese patients
treated for Venous-Thrombo-Embolism (VTE) due to the paucity of prospective and …

Effectiveness and safety of direct oral anticoagulants versus warfarin in obese patients with acute venous thromboembolism

JC Coons, L Albert, A Bejjani… - … : The Journal of Human …, 2020 - Wiley Online Library
Study Objective Studies on the use of direct oral anticoagulants (DOACs) in obese patients
are limited. Current guidelines advise against DOAC use in patients with a body weight …

Real life results of direct-acting oral anticoagulants recommended-dose in obese vs normal-weight patients with venous thromboembolism

JA Rueda-Camino, R Barba, S Otálora… - Thrombosis …, 2024 - Elsevier
Background There is scarce evidence on the effectiveness and safety of recommended-
dose direct acting oral anticoagulants (DOACs) in obese patients with venous …

Anticoagulant therapies and outcomes in obese patients with acute venous thromboembolism

S Quan, J Smith, C Wu, SL Koshman, B Nguyen… - Thrombosis …, 2020 - Elsevier
Abstract Background Direct oral anticoagulants (DOACs) are recommended in preference to
traditional anticoagulants (LMWH±warfarin) for treating acute venous thromboembolism …

[引用][C] Effect of extremes of body weight on drug level in patient treated with standard dose of rivaroxaban for venous thromboembolism; real life experience

DRJ Arachchillage, R Reynolds… - Thrombosis …, 2016 - thrombosisresearch.com
Venous thromboembolism (VTE) is a leading cause of morbidity and mortality worldwide.
Appropriate anticoagulation is crucial in the treatment and prevention of recurrent VTE …