Background Condition-specific measures are frequently used to assess the health-related
quality of life of people with multiple sclerosis (MS). Such measures are unsuitable for use in …

Objective In economic evaluation, health outcomes are commonly quantified using quality-
adjusted life-years (QALYs) derived from the preferences of a sample of the general …

Background Increasingly, generic preference-based measures of health-related quality of
life (HRQOL) are used to estimate quality-adjusted life-years to inform resource allocation …

Abstract Objectives The 29-item Multiple Sclerosis Impact Scale (MSIS-29) is a
psychometrically validated patient-reported outcome measure increasingly used in trials of …

Background: Walking impairment has a major influence on the quality of life of people with
multiple sclerosis (MS). The Multiple Sclerosis Walking Scale (MSWS-12) assesses the …

Background A major debate in the quality-adjusted life-year (QALY) literature concerns
whose preferences should be used to estimate health state values (HSVs) and to calculate …

abstract Objectives To estimate health state utility values (HSUVs) for multiple sclerosis (MS)
by key demographic and clinical characteristics. Methods Data from a UK prospective …

Purpose In multiple sclerosis (MS), the use of preference-based measures is limited to
generic measures such as Health Utilities Index Mark 2 and 3, the EQ-5D and the SF-6D …

Background: Increasing use of the Quality-Adjusted Life-Year to inform resource allocation
decision-making has highlighted the importance of relating clinical and health-related …

Background Health-related quality of life (HRQL) in persons with multiple sclerosis (MS) who
reside within the community relative to the general population is largely unknown. Data from …