Tumor cell-derived exosome-targeted dendritic cells stimulate stronger CD8+ CTL responses and antitumor immunities

Y Yao, L Chen, W Wei, X Deng, L Ma, S Hao - Biochemical and biophysical …, 2013 - Elsevier
Tumor cell-derived exosomes (TEX) have been widely used to induce antitumor immune
responses in animal models and clinical trials. However, the efficiency of the antitumor …

Intradermal vaccination of dendritic cell–derived exosomes is superior to a subcutaneous one in the induction of antitumor immunity

S Hao, Z Ye, J Yang, O Bai, J Xiang - Cancer biotherapy & …, 2006 - liebertpub.com
Because dendritic cell (DC)-derived exosomes (EXO) harbor many important DC molecules
involved in inducing immune responses, EXO-based vaccines have been extensively used …

[HTML][HTML] Dendritic cells loaded with tumor derived exosomes for cancer immunotherapy

H Liu, L Chen, Y Peng, S Yu, J Liu, L Wu, L Zhang… - Oncotarget, 2018 - ncbi.nlm.nih.gov
Exosomes are vesicles that can be secreted by many types of cell and released into the
extracellular space. Studies have found that tumor derived exosomes (TEXs) can promote …

TGF-β1-silenced leukemia cell-derived exosomes target dendritic cells to induce potent anti-leukemic immunity in a mouse model

F Huang, J Wan, S Hao, X Deng, L Chen… - Cancer Immunology …, 2017 - Springer
Tumor-derived exosomes (TEX) can induce a specific antitumor immune response and have
been developed as a promising tumor vaccine. Despite promising preclinical data, TEX …

Dendritic cell-derived exosomes may be a tool for cancer immunotherapy by converting tumor cells into immunogenic targets

GG Romagnoli, BB Zelante, PA Toniolo… - Frontiers in …, 2015 - frontiersin.org
Dendritic cells (DCs) have been attracting attention in cancer immunotherapy because of
their role in inducing and modulating effective immune responses. Besides the direct contact …

The exosomes in tumor immunity

Y Liu, Y Gu, X Cao - Oncoimmunology, 2015 - Taylor & Francis
Exosomes are a kind of nanometric membrane vesicles and can be released by almost all
kinds of cells, including cancer cells. As the important mediators in intercellular …

Tumor Necrosis Factor Gene-Engineered J558 Tumor Cell–Released Exosomes Stimulate Tumor Antigen P1A-Specific CD8+ CTL Responses and Antitumor …

Y Xie, O Bai, H Zhang, W Li, J Xiang - Cancer Biotherapy and …, 2010 - liebertpub.com
Exosomes (EXOs) derived from tumor cells have been used to stimulate antitumor immune
responses. It has been demonstrated that EXO released by tumor cells engineered to …

Dendritic cell-derived exosomes in cancer immunotherapy

S Luo, J Chen, F Xu, H Chen, Y Li, W Li - Pharmaceutics, 2023 - mdpi.com
Exosomes are nanoscale vesicles released by diverse types of cells for complex
intercellular communication. Numerous studies have shown that exosomes can regulate the …

Cancer immunotherapy by exosome-based vaccines

S Hao, T Moyana, J Xiang - Cancer biotherapy & …, 2007 - liebertpub.com
Exosomes (EXOs) are nanometer-sized membrane vesicles secreted from epithelial and
hematopoietic cells. They display a spectrum of molecules involved in immune responses …

[PDF][PDF] Cancer immunotherapy using dendritic cell-derived exosomes

S Amigorena - MEDICINA-BUENOS AIRES-, 2000 - medicinabuenosaires.com
Dendritic cells (DCs) are the most potent antigen presenting cells and the only ones capable
of inducing primary cytotoxic immune responses. We found that DCs secrete a population of …