Treatment outcomes in a cohort of patients with mucosal‐predominant pemphigus vulgaris

S Ojaimi, K O'Connor, MW Lin, M Schifter… - Internal Medicine …, 2015 - Wiley Online Library
Background Pemphigus vulgaris (PV) is a rare autoimmune blistering condition. Treatment
typically combines corticosteroids with another immunosuppressive agent, such as …

Comparing Clinical Outcomes of Steroid-Sparing Therapy With Rituximab Versus Rituximab Alone in Pemphigus.

DE Mustin, EF Cole, R Leibowitz… - Journal of Drugs in …, 2024 - europepmc.org
Background Previous clinical trials have demonstrated that rituximab therapy combined with
conventional steroid-sparing therapy (SST) has increased rates of disease control for …

Retrospective analysis of a single‐center clinical experience toward development of curative treatment of 123 pemphigus patients with a long‐term follow‐up: efficacy …

SA Grando - International Journal of Dermatology, 2019 - Wiley Online Library
Background Pemphigus vulgaris (PV) is a life‐long IgG autoantibody‐mediated blistering
disease affecting the mucosal surfaces lined by the stratified epithelium (oral, nasal, genital) …

Rituximab for patients with refractory mucous membrane pemphigoid

C Le Roux-Villet, C Prost-Squarcioni… - Archives of …, 2011 - jamanetwork.com
Background Mucous membrane pemphigoid (MMP) still represents a potentially life-and
sight-threatening disease. In a subset of patients with severe MMP, conventional …

Clinical effect of omalizumab as an adjuvant treatment to rituximab in patient with refractory bullous pemphigoid

IJ Kwon, T Kim, DS Yoo, S Min… - The Journal of …, 2023 - Wiley Online Library
Patients with refractory bullous pemphigoid (BP) achieve remission after rituximab treatment
but require high‐dose systemic corticosteroids until the remission. The aim of this …

Rituximab exhibits a better safety profile when used as a first line of treatment for pemphigus vulgaris: a retrospective study

Z Aryanian, K Balighi, M Daneshpazhooh… - International …, 2021 - Elsevier
Background Pemphigus is an autoimmune disease that is challenging to treat and has few
available therapeutic options. Recently, several studies have demonstrated that rituximab …

Prolonged treatment with rituximab in patients with refractory pemphigus vulgaris

MV Barrera, MV Mendiola, RJ Bosch… - Journal of …, 2007 - Taylor & Francis
Objectives: Recent reports have documented swift responses in refractory pemphigus
vulgaris to rituximab, a monoclonal anti‐CD20 antibody. Nevertheless, no standard protocol …

Autoimmune blistering diseases: promising agents in clinical trials

H Olbrich, CD Sadik, E Schmidt - Expert Opinion on Investigational …, 2023 - Taylor & Francis
Introduction Treatment options for autoimmune bullous diseases (AIBD) are currently limited
to corticosteroids and traditional immunomodulants and immunosuppressants that are …

Mucosal involvement is a risk factor for poor clinical outcomes and relapse in patients with pemphigus treated with rituximab

SI Cho, JW Kim, JS Lim, JH Chung - Dermatologic therapy, 2019 - Wiley Online Library
Many studies have reported the outcome of rituximab use in pemphigus but studies
regarding the clinical risk factors for poor clinical outcomes or relapse are lacking. To clarify …

Rituximab in autoimmune pemphigoid diseases: indications, optimized regimens, and practice gaps

RM Thomas, A Colon, K Motaparthi - Clinics in dermatology, 2020 - Elsevier
Rituximab is a monoclonal antibody targeting CD20 on B cells with proven efficacy for
pemphigus vulgaris, now an FDA-approved indication. Other autoimmune bullous diseases …