Medication safety in pregnancy: With focus on analgesics and neurodevelopmental outcomes in children

JN Trønnes - 2022 - duo.uio.no
Eight out of ten women report having used medicines in pregnancy. Though painkillers are
amongst the most frequently used medicines, little is known about their long-term effects on …

Childhood outcomes after prenatal exposure to analgesics or antibiotics

S Hjorth - 2021 - duo.uio.no
'Can I take this medication now that I am pregnant?', is a question that many health care
professionals have met during consultations with pregnant women. Between 60 and 96% of …

Analgesics in pregnancy: an update on use, safety and pharmacokinetic changes in drug disposition

HR Price, AC Collier - Current Pharmaceutical Design, 2017 - ingentaconnect.com
Background: Although medications should only be prescribed in pregnancy if benefits to the
mother outweigh the risk to the fetus, drug use in pregnancy especially prescribed and over …

Prescribed opioid analgesics in early pregnancy and the risk of congenital anomalies: a population-based cohort study

AC Bowie, MM Werler, MP Velez, W Li, A Camden… - CMAJ, 2022 - Can Med Assoc
Background: Recent data suggest an increased risk of congenital anomalies with prenatal
exposure to opioid analgesics. We sought to further quantify the risk of anomalies after …

Maternal over-the-counter analgesics use during pregnancy and adverse perinatal outcomes: cohort study of 151 141 singleton pregnancies

A Zafeiri, EA Raja, RT Mitchell, DC Hay… - BMJ open, 2022 - bmjopen.bmj.com
Objectives To identify any associations between in utero exposure to five over-the-counter
(non-prescription) analgesics (paracetamol, ibuprofen, aspirin, diclofenac, naproxen) and …

[HTML][HTML] Use and validity of child neurodevelopment outcome measures in studies on prenatal exposure to psychotropic and analgesic medications–A systematic …

S Hjorth, R Bromley, E Ystrom, A Lupattelli, O Spigset… - PLoS …, 2019 - journals.plos.org
In recent years there has been increased attention to child neurodevelopment in studies on
medication safety in pregnancy. Neurodevelopment is a multifactorial outcome that can be …

Neurodevelopmental problems at 18 months among children exposed to paracetamol in utero: a propensity score matched cohort study

R Vlenterie, ME Wood, RE Brandlistuen… - International journal …, 2016 - academic.oup.com
Background: Previous studies showed that children exposed to paracetamol during fetal life
might have an increased risk of neurodevelopmental problems. Since paracetamol is one of …

P–732 Maternal over-the-counter analgesics use during pregnancy and adverse perinatal outcomes: cohort study of 151,141 singleton pregnancies

A Zafeiri, EA Raja, DC Hay, RT Mitchell… - Human …, 2021 - academic.oup.com
Study question Is in utero exposure to five over-the-counter (non-prescription) analgesics
(paracetamol, ibuprofen, aspirin, diclofenac, naproxen) associated with offspring health …

Analysis of prenatal exposure to opioid analgesics and scholastic skills in children in fifth grade in Norway

JN Trønnes, A Lupattelli, E Ystrom… - JAMA Network …, 2022 - jamanetwork.com
Importance Few studies have examined the neurodevelopmental consequences of prenatal
exposure to opioid analgesics. Therefore, it is necessary to gain knowledge to inform clinical …

[HTML][HTML] Analgesic drug use in pregnancy and neurodevelopment outcomes: an umbrella review

J Kwok, E Luedecke, HA Hall, AL Murray… - … & Biobehavioral Reviews, 2022 - Elsevier
Emerging evidence from reviews suggests that analgesic drug exposure during pregnancy
may contribute to child neurodevelopment outcomes. A comprehensive overview of existing …