Biodegradable poly (lactic-co-glycolic) acid (PLGA) nanoparticles incorporating cisplatin
have been developed to evaluate its in vivo efficacy in tumor-bearing mice. In vitro study …

The goal of the present study is to utilize cis-diamminedichloroplatinum (cisplatin) loaded
polymer nanoparticles (NPs) to give a controlled, extended, and local drug therapy for the …

Nanoparticle drug carriers consist of solid biodegradable particles in size ranging from 10 to
1000 nm (50–300 nm generally). They cannot freely diffuse through the blood-brain barrier …

Amine-functionalized poly (lactic-co-glycolic acid)(PLGA-NH 2) nanoparticles (NPs) were
developed for the delivery of phloretin. PLGA-NH 2/phloretin NPs with 237 nm mean …

Brain injury is a common cause for physical and emotional effects to the large number of
populations. Moreover, glioblastoma is the tumor in brain with no possible treatment leading …

Nose-to-brain delivery is a promising approach to target drugs into the brain, avoiding the
blood-brain barrier and other drawbacks related to systemic absorption, and enabling an …

The object of the present study was to investigate the glioma targeting propensity of folic
acid (F) decorated polymer–lipid hybrid nanoparticles (PLNs) encapsulating cyclo-[Arg-Gly …

Poly (lactide-co-glycolide)(PLGA) nanoparticles coated with poloxamer 188 (Pluronic® F-
68) or polysorbate 80 (Tween® 80) enable an efficient brain delivery of the drugs after …

The particle size (PS) and encapsulation efficiency (EE%) of drug-loaded nanoparticles
(NPs) may inhibit their cellular uptake and lead to possible leakage of the drug into the …

Purpose: The aim of this study was to investigate the ability of PEGylated poly (d, l-lactide-co-
glycolide) nanoparticles (NPs) to deliver Docetaxel (DTX)(an anticancer agent) to solid …