Effects of chronic sugar consumption on lipid accumulation and autophagy in the skeletal muscle
D De Stefanis, R Mastrocola, D Nigro, P Costelli… - European journal of …, 2017 - Springer
Purpose In recent years, the increasing consumption of soft drinks containing high-fructose
corn syrup or sucrose has caused a rise in fructose intake, which has been related to the …
corn syrup or sucrose has caused a rise in fructose intake, which has been related to the …
[HTML][HTML] Effect of a single bout of exercise on autophagy regulation in skeletal muscle of high-fat high-sucrose diet-fed mice
Background Autophagy maintains metabolic homeostasis of muscles, and its impairment
may cause muscle dysfunction. Exercise can improve muscle dysfunction induced by long …
may cause muscle dysfunction. Exercise can improve muscle dysfunction induced by long …
[HTML][HTML] The effects of exercise and restriction of sugar-sweetened beverages on muscle function and autophagy regulation in high-fat high-sucrose-fed obesity mice
Background Autophagy maintains muscle mass and healthy skeletal muscles. Several
recent studies have associated sugar-sweetened beverage (SSB) consumption with …
recent studies have associated sugar-sweetened beverage (SSB) consumption with …
Extremely rapid increase in fatty acid transport and intramyocellular lipid accumulation but markedly delayed insulin resistance after high fat feeding in rats
A Bonen, SS Jain, LA Snook, XX Han, Y Yoshida… - Diabetologia, 2015 - Springer
Aims/hypothesis The mechanisms for diet-induced intramyocellular lipid accumulation and
its association with insulin resistance remain contentious. In a detailed time-course study in …
its association with insulin resistance remain contentious. In a detailed time-course study in …
Fructose overfeeding in first‐degree relatives of type 2 diabetic patients impacts energy metabolism and mitochondrial functions in skeletal muscle
K Seyssel, E Meugnier, KA Lê, C Durand… - Molecular nutrition & …, 2016 - Wiley Online Library
Scope The aim of the study was to assess the effects of a high‐fructose diet (HFrD) on
skeletal muscle transcriptomic response in healthy offspring of patients with type 2 diabetes …
skeletal muscle transcriptomic response in healthy offspring of patients with type 2 diabetes …
Chronic muscle stimulation improves insulin sensitivity while increasing subcellular lipid droplets and reducing selected diacylglycerol and ceramide species in obese …
GP Holloway, XX Han, SS Jain, A Bonen, A Chabowski - Diabetologia, 2014 - Springer
Aims/hypothesis Although insulin resistance has been associated with accumulations of
specific intramuscular fatty acids and altered subcellular localisation of lipid droplets, these …
specific intramuscular fatty acids and altered subcellular localisation of lipid droplets, these …
Skeletal intramyocellular lipid metabolism and insulin resistance
Y Li, S Xu, X Zhang, Z Yi, S Cichello - Biophysics reports, 2015 - Springer
Lipids stored in skeletal muscle cells are known as intramyocellular lipid (IMCL). Disorders
involving IMCL and its causative factor, circulatory free fatty acids (FFAs), induce a toxic state …
involving IMCL and its causative factor, circulatory free fatty acids (FFAs), induce a toxic state …
Autophagy is not involved in lipid accumulation and the development of insulin resistance in skeletal muscle
MG Morales-Scholz, C Swinton, RM Murphy… - Biochemical and …, 2021 - Elsevier
Objective To investigate the effect of high fat diet-induced insulin resistance on autophagy
markers in the liver and skeletal muscle of mice in the fasted state and following an oral …
markers in the liver and skeletal muscle of mice in the fasted state and following an oral …
Adaptive metabolic response to 4 weeks of sugar-sweetened beverage consumption in healthy, lightly active individuals and chronic high glucose availability in …
F Sartor, MJ Jackson, C Squillace, A Shepherd… - European journal of …, 2013 - Springer
Purpose Chronic sugar-sweetened beverage (SSB) consumption is associated with obesity
and type 2 diabetes mellitus (T2DM). Hyperglycaemia contributes to metabolic alterations …
and type 2 diabetes mellitus (T2DM). Hyperglycaemia contributes to metabolic alterations …
Lipid-induced insulin resistance in skeletal muscle: the chase for the culprit goes from total intramuscular fat to lipid intermediates, and finally to species of lipid …
SM Kitessa, MY Abeywardena - Nutrients, 2016 - mdpi.com
The skeletal muscle is the largest organ in the body. It plays a particularly pivotal role in
glucose homeostasis, as it can account for up to 40% of the body and for up to 80%–90% of …
glucose homeostasis, as it can account for up to 40% of the body and for up to 80%–90% of …