Pre-clinical evaluation of novel pharmacological targets for the treatment of obesity and eating disorders: focus on Oleoylethanolamide and the oxytocinergic system

B Eramo - 2024 - iris.uniroma1.it
Overweight, obesity and eating disorders, such as anorexia nervosa (AN), are complex
conditions, influenced by a variety of factors, including genetic, environmental …

Prospects for new drugs to treat aberrant eating patterns: possible role of Oleoylethanolamide

M Friuli - 2022 - iris.uniroma1.it
Obesity is a complex pathology that occurs when energy intake exceeds energy expenditure
and is characterized by the accumulation of dysfunctional adipose tissue which triggers …

Oleoylethanolamide: a new player in peripheral control of energy metabolism. Therapeutic implications

FJ Pavón, A Serrano, M Romero-Cuevas… - Drug Discovery Today …, 2010 - Elsevier
The incidence of obesity and related metabolic disorders is currently increasing at an
alarming rate in modern society. Therefore, the development of effective antiobesity …

Oleoylethanolamide: A fat ally in the fight against obesity

JD Brown, EK Azari, JE Ayala - Physiology & behavior, 2017 - Elsevier
Obesity is a pandemic, gateway disease that has thrived in modern, sedentary, high calorie-
eating societies. Left unchecked, obesity and obesity-related diseases will continue to …

Oleoylethanolamide: a new player in energy metabolism control. Role in food intake

P Dipasquale, A Romano, S Cianci, L Righetti… - Drug discovery today …, 2010 - Elsevier
Oleoylethanolamide (OEA) is a lipid amide produced by enterocytes upon the absorption of
dietary fat and participates in the induction of satiety. Through indirect pathways, probably …

Oleoylethanolamide: A novel pharmaceutical agent in the management of obesity‐an updated review

P Laleh, K Yaser, O Alireza - Journal of Cellular Physiology, 2019 - Wiley Online Library
Obesity as a multifactorial disorder has been shown a dramatically growing trend recently.
Besides genetic and environmental factors, dysregulation of the endocannabinoid system …

A systematic review of the effects of oleoylethanolamide, a high‐affinity endogenous ligand of PPAR‐α, on the management and prevention of obesity

H Tutunchi, M Saghafi‐Asl… - Clinical and …, 2020 - Wiley Online Library
Along with an increase in overweight and obesity among all age groups, the development of
efficacious and safe anti‐obesity strategies for patients, as well as health systems, is critical …

Oleoylethanolamide: effects on hypothalamic transmitters and gut peptides regulating food intake

A Serrano, FJ Pavón, S Tovar, F Casanueva… - …, 2011 - Elsevier
Recently, it has been described the role of fatty acid ethanolamides in the control of feeding
behavior. Oleoylethanolamide (OEA) is a member of this family of lipid mediators regulating …

Action Profile of the Antiobesity Drug Candidate Oleoyl‐Estrone in Rats

S Strassburg, PT Pfluger, N Chaudhary, P Tso… - …, 2010 - Wiley Online Library
Oleoyl‐estrone (OE) has been presented as a potential antiobesity therapeutic, but the
published series of studies from one laboratory has not yet been independently confirmed …

Oleoylethanolamide inhibits food intake in free-feeding rats after oral administration

F Oveisi, S Gaetani, KTP Eng, D Piomelli - Pharmacological research, 2004 - Elsevier
Oleoylethanolamide (OEA) is an endogenous lipid that contributes in important ways to the
peripheral regulation of food intake. When administered intraperitoneally, OEA is a potent …