Iron, infections, and anemia of inflammation
RL Jurado - Clinical infectious diseases, 1997 - academic.oup.com
Iron is essential to all microorganisms. To obtain iron from the very low concentrations
present in their environment, microorganisms have developed sophisticated mechanisms …
present in their environment, microorganisms have developed sophisticated mechanisms …
Iron and infection: competition between host and microbes for a precious element
JJM Marx - Best practice & research Clinical haematology, 2002 - Elsevier
During infection microbes attack host tissues, causing damage to specific organs, sepsis or
even death. For proliferation microbes desperately need iron for which they have to compete …
even death. For proliferation microbes desperately need iron for which they have to compete …
[HTML][HTML] Iron in infection and immunity
M Nairz, G Weiss - Molecular Aspects of Medicine, 2020 - Elsevier
Iron is an essential micronutrient for virtually all living cells. In infectious diseases, both
invading pathogens and mammalian cells including those of the immune system require iron …
invading pathogens and mammalian cells including those of the immune system require iron …
The role of iron in the immune response to bacterial infection
BJ Cherayil - Immunologic research, 2011 - Springer
My laboratory has been interested for some time in the influence of iron, a nutrient that is
essential for both microbial pathogens and their mammalian hosts, on the course of …
essential for both microbial pathogens and their mammalian hosts, on the course of …
[HTML][HTML] Iron metabolism and the innate immune response to infection
EE Johnson, M Wessling-Resnick - Microbes and infection, 2012 - Elsevier
Host antimicrobial mechanisms reduce iron availability to pathogens. Iron proteins
influencing the innate immune response include hepcidin, lactoferrin, siderocalin …
influencing the innate immune response include hepcidin, lactoferrin, siderocalin …
Iron and microbial infection
UE Schaible, SHE Kaufmann - Nature Reviews Microbiology, 2004 - nature.com
The use of iron as a cofactor in basic metabolic pathways is essential to both pathogenic
microorganisms and their hosts. It is also a pivotal component of the innate immune …
microorganisms and their hosts. It is also a pivotal component of the innate immune …
Iron and innate antimicrobial immunity—depriving the pathogen, defending the host
M Nairz, S Dichtl, A Schroll, D Haschka… - Journal of Trace …, 2018 - Elsevier
The acute-phase response is triggered by the presence of infectious agents and danger
signals which indicate hazards for the integrity of the mammalian body. One central feature …
signals which indicate hazards for the integrity of the mammalian body. One central feature …
Iron, anemia, and infection
T Walter, M Olivares, F Pizarro, C Muñoz - Nutrition reviews, 1997 - academic.oup.com
The data on the relationship between iron deficiency and infection are conflicting. Some
researchers conclude that mild iron deficiency is beneficial for immunity, whereas others …
researchers conclude that mild iron deficiency is beneficial for immunity, whereas others …
Iron in innate immunity: starve the invaders
T Ganz - Current opinion in immunology, 2009 - Elsevier
Iron is essential for nearly all living organisms. Innate immunity effectively restricts iron
availability to microbial invaders. Some microbes have evolved effective countermeasures …
availability to microbial invaders. Some microbes have evolved effective countermeasures …
The significance of iron in infection
JJ Bullen - Reviews of infectious diseases, 1981 - academic.oup.com
The iron-binding proteins transferrin and lactoferrin restrict the amount of ionic iron available
in body fluids to 10-18 M. This amount is insufficient for normal bacterial growth, and …
in body fluids to 10-18 M. This amount is insufficient for normal bacterial growth, and …