Treatable traits in COPD–a proposed approach

J Cardoso, AJ Ferreira, M Guimarães… - … Journal of Chronic …, 2021 - Taylor & Francis
The well-recognized individual heterogeneity within COPD patients has led to a growing
interest in greater personalization in the approach of these patients. Thus, the treatable traits …

The use of treatable traits to address COPD complexity and heterogeneity and to inform the care

K Duszyk, RF McLoughlin, PG Gibson, VM McDonald - Breathe, 2021 - Eur Respiratory Soc
COPD is complex and heterogeneous with respect to its aetiology, clinical presentation,
phenotypes and biological mechanisms. Despite this, COPD is still diagnosed and treated …

Can Treatable Traits Be the Approach to Addressing the Complexity and Heterogeneity of COPD?

M Cazzola, P Rogliani, F Blasi - International Journal of Chronic …, 2023 - Taylor & Francis
The complexity of COPD implies the need to identify groups of patients with similar clinical
characteristics and prognosis or treatment requirements. This is why much attention has …

Current approaches for phenotyping as a target for precision medicine in COPD management

JL Lopez-Campos, S Centanni - COPD: Journal of Chronic …, 2018 - Taylor & Francis
The study of airway diseases continues to present several challenges for modern medicine.
The different disease presentations with variables and overlapping features may result in a …

The treatable traits approach to adults with obstructive airways disease in primary and secondary care

M Thomas, R Beasley - Respirology, 2023 - Wiley Online Library
The treatable traits approach is based on the recognition that the different clinical
phenotypes of asthma and chronic obstructive airways disease (COPD) are a …

Moving Towards Patient-Centered Medicine for COPD Management: Multidimensional Approaches versus Phenotype-Based Medicine—A Critical View

JL Lopez-Campos, V Bustamante… - COPD: Journal of …, 2014 - Taylor & Francis
For decades, chronic obstructive pulmonary disease (COPD) has been considered a
relentlessly progressive disease in which the deterioration of lung function is associated with …

[HTML][HTML] Moving towards a treatable traits model of care for the management of obstructive airways diseases

A Agusti, N Barnes, AA Cruz, PG Gibson, LG Heaney… - Respiratory …, 2021 - Elsevier
Asthma and chronic obstructive pulmonary disease (COPD) are two prevalent chronic
airways diseases. Both are complex and heterogeneous. Traditionally, clinical guidelines …

Phenotyping before starting treatment in COPD?

N Siafakas, A Corlateanu, E Fouka - COPD: Journal of Chronic …, 2017 - Taylor & Francis
ABSTRACT Chronic Obstructive Pulmonary Disease (COPD) is a heterogeneous and
complex disease with great morbidity and mortality. Despite the new developments in the …

Personalized medicine: chronic obstructive pulmonary disease treatment

JL Corhay - Revue Medicale de Liege, 2015 - europepmc.org
Chronic obstructive pulmonary disease (COPD) is a complex disorder and not all patients
respond to all available drugs. The importance of personalized treatment in COPD is …

Comorbid conditions in chronic obstructive pulmonary disease: Potential therapeutic targets for unmet needs

K Matsunaga, M Harada, J Suizu, K Oishi… - Journal of Clinical …, 2020 - mdpi.com
The management of chronic obstructive pulmonary disease (COPD) has improved
significantly due to advances in therapeutic agents, but it has also become apparent that …