New targeting strategies in drug therapy of inflammatory bowel disease: mechanistic approaches and opportunities

O Wolk, S Epstein, V Ioffe-Dahan… - Expert Opinion on …, 2013 - Taylor & Francis
Introduction: Inflammatory bowel disease (IBD) is an exceptional scenario with regard to
drug targeting, as oral administration has the potential to deliver the drug directly to the site …

Drug targeting strategies for the treatment of inflammatory bowel disease: a mechanistic update

A Dahan, GL Amidon… - Expert review of clinical …, 2010 - Taylor & Francis
The therapeutic management of inflammatory bowel disease (IBD) represents the perfect
scenario for drug targeting to the site (s) of action. While existing formulation-based targeting …

Emerging pharmacotherapy for inflammatory bowel diseases

H Luo, G Cao, C Luo, D Tan, CT Vong, Y Xu… - Pharmacological …, 2022 - Elsevier
Inflammatory bowel disease (IBD) refers to a gamut of disorders that are characterized by
chronic intestinal inflammation, including ulcerative colitis (UC) and Crohn's disease (CD) …

[HTML][HTML] Novel drug delivery systems for inflammatory bowel disease

F Yasmin, H Najeeb, S Shaikh… - World Journal of …, 2022 - ncbi.nlm.nih.gov
Inflammatory bowel disease (IBD) is a chronic illness characterized by relapsing
inflammation of the intestines. The disorder is stratified according to the severity and is …

Current scenario in inflammatory bowel disease: drug development prospects

S Chandel, A Prakash, B Medhi - Pharmacological Reports, 2015 - Elsevier
Background Inflammatory bowel disease (IBD) pathophysiology have led to the
development of various compounds that might ameliorate the disease process. Recently …

[HTML][HTML] Site-specific targeted drug delivery systems for the treatment of inflammatory bowel disease

X Li, C Lu, Y Yang, C Yu, Y Rao - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Inflammatory bowel disease (IBD) includes Crohn's disease and ulcerative colitis and
manifests as a complex and dysregulated immune response. To date, there is no cure for …

Novel drug delivery strategies for the treatment of inflammatory bowel disease

F Kesisoglou, EM Zimmermann - Expert opinion on drug delivery, 2005 - Taylor & Francis
Inflammatory bowel disease (IBD) encompasses two idiopathic inflammatory diseases of the
intestinal tract: Crohn's disease and ulcerative colitis. Existing therapy for IBD consists …

[HTML][HTML] The current state of the art for biological therapies and new small molecules in inflammatory bowel disease

S Paramsothy, AK Rosenstein, S Mehandru… - Mucosal …, 2018 - Elsevier
The emergence of biologic therapies is arguably the greatest therapeutic advance in the
care of inflammatory bowel disease (IBD) to date, allowing directed treatments targeted at …

New insights of oral colonic drug delivery systems for inflammatory bowel disease therapy

AH Teruel, I Gonzalez-Alvarez, M Bermejo… - International journal of …, 2020 - mdpi.com
Colonic Drug Delivery Systems (CDDS) are especially advantageous for local treatment of
inflammatory bowel diseases (IBD). Site-targeted drug release allows to obtain a high drug …

Drug delivery to the inflamed intestinal mucosa–targeting technologies and human cell culture models for better therapies of IBD

O Hartwig, MAS Boushehri, KS Shalaby… - Advanced Drug Delivery …, 2021 - Elsevier
Current treatment strategies for inflammatory bowel disease (IBD) seek to alleviate the
undesirable symptoms of the disorder. Despite the higher specificity of newer generation …