Acceptor Planarization and Donor Rotation: A Facile Strategy for Realizing Synergistic Cancer Phototherapy via Type I PDT and PTT

L Feng, C Li, L Liu, Z Wang, Z Chen, J Yu, W Ji… - ACS …, 2022 - ACS Publications
Tumor hypoxia seriously impairs the therapeutic outcomes of type II photodynamic therapy
(PDT), which is highly dependent upon tissue oxygen concentration. Herein, a facile strategy …

Type I photosensitizers revitalizing photodynamic oncotherapy

D Chen, Q Xu, W Wang, J Shao, W Huang, X Dong - Small, 2021 - Wiley Online Library
Photodynamic therapy (PDT) has shown great potential for tumor treatment with merits of
non‐invasiveness, high selectivity, and minimal side effects. However, conventional type II …

π Bridge Engineering-Boosted Dual Enhancement of Type-I Photodynamic and Photothermal Performance for Mitochondria-Targeting Multimodal Phototheranostics …

L Fang, Q Meng, Y Zhang, R Su, F Xing, H Yang… - ACS …, 2023 - ACS Publications
Designing mitochondria-targeting phototheranostic agents (PTAs), which can
simultaneously possess exceptional and balanced type-I photodynamic therapy (PDT) and …

Good steel used in the blade: well‐tailored type‐I photosensitizers with aggregation‐induced emission characteristics for precise nuclear targeting photodynamic …

M Kang, Z Zhang, W Xu, H Wen, W Zhu… - Advanced …, 2021 - Wiley Online Library
Photodynamic therapy (PDT) has long been recognized to be a promising approach for
cancer treatment. However, the high oxygen dependency of conventional PDT dramatically …

A nanoplatform for mild-temperature photothermal and type I & II photodynamic therapy in the NIR-II biowindow

B Lu, Z Zhang, Y Huang, Y Zhang, J Wang… - Chemical …, 2022 - pubs.rsc.org
In the current work, we synthesized an A–D–A smallmolecule photosensitizer, denoted as
DPTTIC, and a dual PEG-functionalized pillararene, denoted as WP5-8C-2PEG, and used …

A mitochondrion-targeting two-photon photosensitizer with aggregation-induced emission characteristics for hypoxia-tolerant photodynamic therapy

Y Jiang, W Zhu, Z Xu, Z Zhang, S Tang, M Fan… - Chemical Engineering …, 2022 - Elsevier
In recent years, two-photon photodynamic therapy (TP-PDT) has received extensive
attention in cancer treatment owing to its unique advantages of deep tissue penetration and …

[HTML][HTML] Molecular design of conjugated small molecule nanoparticles for synergistically enhanced PTT/PDT

W Shao, C Yang, F Li, J Wu, N Wang, Q Ding, J Gao… - Nano-Micro Letters, 2020 - Springer
Simultaneous photothermal therapy (PTT) and photodynamic therapy (PDT) is beneficial for
enhanced cancer therapy due to the synergistic effect. Conventional materials developed for …

An NIR‐II‐Emissive Photosensitizer for Hypoxia‐Tolerant Photodynamic Theranostics

L Li, C Shao, T Liu, Z Chao, H Chen, F Xiao… - Advanced …, 2020 - Wiley Online Library
As a common feature in a majority of malignant tumors, hypoxia has become the Achilles'
heel of photodynamic therapy (PDT). The development of type‐I photosensitizers that show …

Recent advances in type I organic photosensitizers for efficient photodynamic therapy for overcoming tumor hypoxia

B Lu, L Wang, H Tang, D Cao - Journal of Materials Chemistry B, 2023 - pubs.rsc.org
Photodynamic therapy (PDT) with an oxygen-dependent character is a noninvasive
therapeutic method for cancer treatment. However, its clinical therapeutic effect is greatly …

Highly Efficient Multifunctional Organic Photosensitizer with Aggregation-Induced Emission for In Vivo Bioimaging and Photodynamic Therapy

Y Liao, R Wang, S Wang, Y Xie, H Chen… - … Applied Materials & …, 2021 - ACS Publications
Photosensitizers play a critical role in photodynamic therapy (PDT). Multifunctional organic
nanoparticles (NPs) that possess bright fluorescence in aggregates, high singlet oxygen …