An alternative mechanism of clathrin-coated pit closure revealed by ion conductance microscopy

AI Shevchuk, P Novak, M Taylor, IA Diakonov… - Journal of Cell …, 2012 - rupress.org
Current knowledge of the structural changes taking place during clathrin-mediated
endocytosis is largely based on electron microscopy images of fixed preparations and x-ray …

Understanding living clathrin‐coated pits

JZ Rappoport, SM Simon, A Benmerah - Traffic, 2004 - Wiley Online Library
Most knowledge of clathrin‐mediated endocytosis has been gained by biochemical
fractionation and in vitro assays. Recently, the study of endocytosis has extended into the …

Spatial control of coated-pit dynamics in living cells

I Gaidarov, F Santini, RA Warren, JH Keen - Nature cell biology, 1999 - nature.com
Here we visualize new aspects of the dynamics of endocytotic clathrin-coated pits and
vesicles in mammalian cells by using a fusion protein consisting of green fluorescent protein …

Imaging actin and dynamin recruitment during invagination of single clathrin-coated pits

CJ Merrifield, ME Feldman, L Wan, W Almers - Nature cell biology, 2002 - nature.com
As a final step in endocytosis, clathrin-coated pits must separate from the plasma membrane
and move into the cytosol as a coated vesicle. Because these events involve minute …

Clathrin exchange during clathrin-mediated endocytosis

X Wu, X Zhao, L Baylor, S Kaushal… - The Journal of cell …, 2001 - rupress.org
During clathrin-mediated endocytosis, clathrin-coated pits invaginate to form clathrin-coated
vesicles (CVs). Since clathrin-coated pits are planar structures, whereas CVs are spherical …

Quantifying the dynamic interactions between a clathrin-coated pit and cargo molecules

AV Weigel, MM Tamkun… - Proceedings of the …, 2013 - National Acad Sciences
Clathrin-mediated endocytosis takes place through the recruitment of cargo molecules into a
growing clathrin-coated pit (CCP). Despite the importance of this process to all mammalian …

Coupling between clathrin-coated-pit invagination, cortactin recruitment, and membrane scission observed in live cells

CJ Merrifield, D Perrais, D Zenisek - Cell, 2005 - cell.com
During clathrin-mediated endocytosis, membrane scission marks the isolation of a cargo-
laden clathrin-coated pit (CCP) from the cell exterior. Here we used live-cell imaging of a pH …

Imaging endocytic clathrin structures in living cells

T Kirchhausen - Trends in cell biology, 2009 - cell.com
Our understanding of the clathrin-dependent endocytic pathway owes much to new
visualization techniques. Budding coated pits and clathrin-coated structures are transient …

Cell spreading area regulates clathrin-coated pit dynamics on micropatterned substrate

X Tan, J Heureaux, AP Liu - Integrative biology, 2015 - academic.oup.com
Clathrin-mediated endocytosis (CME) is the most characterized pathway for the endocytic
entry of proteins and lipids at the plasma membrane of eukaryotic cells. Numerous studies …

Flat clathrin lattices: stable features of the plasma membrane

J Grove, DJ Metcalf, AE Knight… - Molecular biology of …, 2014 - Am Soc Cell Biol
Clathrin-mediated endocytosis (CME) is a fundamental property of eukaryotic cells.
Classical CME proceeds via the formation of clathrin-coated pits (CCPs) at the plasma …