The role of reactive oxygen species (ROS) in ischemic and reperfusion (I/R) injury of the
heart has been discussed for more than 40 years. It has been demonstrated that reperfusion …

Reactive oxygen species (ROS) are involved in cardiovascular diseases and, in particular,
in myocardial ischemia and reperfusion. Although the restoration of blood flow is essential …

Myocardial ischemia‐reperfusion (I/R) injury is experienced by individuals suffering from
cardiovascular diseases such as coronary heart diseases and subsequently undergoing …

Reperfusion injury is an inherent response to the restoration of blood flow after ischemia. It is
a complex process involving numerous mechanisms occurring in the intracellular and …

The incidence and mortality of heart disease are the highest among all diseases all over the
world, and are still increasing with a world wide rise in living standards. To find effective …

Reactive oxygen species (ROS) and reactive nitrogen species (RNS) formation increases in
the post-ischemic myocardium and represents a mechanism of post ischemic injury. ROS …

In acute myocardial ischemia (AMI) the optimal treatment is rapid revascularization by
angioplasty or pharmacological thrombolysis. While this is essential to resuscitate the …

Myocardial ischemia is a major cause of morbidity and mortality in the world. Although
restoration of blood flow after prolonged ischemia is essential for cardiomyocytes salvation …

Animal studies have demonstrated that restoration of blood flow to severely ischemic
myocardium is a prerequisite for myocardial salvage. However, it has been shown that the …

Reperfusion of acutely ischemic myocardium is associated with various distinctive
pathophysiologic derangements, which are collectively referred to as reperfusion injury …