[HTML][HTML] Exploration of differentially expressed mRNAs and miRNAs for pediatric acute myeloid leukemia

Q Wang, C Yue, Q Liu, X Che - Frontiers in Genetics, 2022 - frontiersin.org
Background: To establish a comprehensive differential gene profile for pediatric acute
myeloid leukemia patients (pAML) based on two independent databases and verify the …

Comprehensive analysis the potential biomarkers for the high-risk of childhood acute myeloid leukemia based on a competing endogenous RNA network

N Zhang, Y Chen, Y Shen, S Lou, J Deng - Blood Cells, Molecules, and …, 2019 - Elsevier
Acute myeloid leukemia (AML) is a common form of hematological malignancies, the
discovery of non-coding RNA (ncRNA) plays an important role in diverse biological …

[HTML][HTML] Classification of pediatric acute myeloid leukemia based on miRNA expression profiles

A Obulkasim, JE Katsman-Kuipers, L Verboon… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Pediatric acute myeloid leukemia (AML) is a heterogeneous disease with respect to biology
as well as outcome. In this study, we investigated whether known biological subgroups of …

A 4‐microRNA signature for survival prognosis in pediatric and adolescent acute myeloid leukemia

R Zhu, W Lin, W Zhao, F Fan, L Tang… - Journal of cellular …, 2019 - Wiley Online Library
Acute myeloid leukemia (AML) is a hematologic malignancy with significant molecular
heterogeneity. MicroRNAs (miRNAs) play a critical role in AML diagnosis, pathogenesis …

The expression and functional study of miR-181a in pediatric acute lymphoblastic leukemia

W Liao, X Liu, H Peng, L Xu - Zhonghua xue ye xue za zhi …, 2015 - europepmc.org
Objective To investigate the expression of miR-181a in bone marrow (BM) samples of
pediatric acute lymphoblastic leukemia (ALL) and explore the mechanism of miR-181a on …

Up-regulated miR-155 is associated with poor prognosis in childhood acute lymphoblastic leukemia and promotes cell proliferation targeting ZNF238

C Liang, Y Li, LN Wang, XL Zhang, JS Luo, CJ Peng… - …, 2021 - Taylor & Francis
Objectives Acute lymphoblastic leukemia (ALL) is one of the most common malignancies in
children. Our aim was to identify a novel miRNA that can predict prognosis of childhood ALL …

Identification of MiR-93-5p Targeted Pathogenic Markers in Acute Myeloid Leukemia through Integrative Bioinformatics Analysis and Clinical Validation

J Wang, Y Wu, MN Uddin, J Hao, R Chen… - Journal of …, 2021 - Wiley Online Library
Acute myeloid leukemia (AML) is a type of hematological malignancy with diverse genetic
pathogenesis. Identification of the miR-93-5p targeted pathogenic markers could be useful …

[HTML][HTML] MicroRNA-107 promotes apoptosis of acute myelocytic leukemia cells by targeting RAD51

F Huang, W Tang, Y Lei - Archives of medical science: AMS, 2021 - ncbi.nlm.nih.gov
Results Acute myelocytic leukemia-associated genes (n= 197) and miRNAs (n= 1701) were
retrieved from the database, the interaction network of miRNA-mRNA was constructed and …

[HTML][HTML] A 3-miRNA signature predicts prognosis of pediatric and adolescent cytogenetically normal acute myeloid leukemia

R Zhu, W Zhao, F Fan, L Tang, J Liu, T Luo, J Deng… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Acute myeloid leukemia is a hematologic malignancy with significant molecular
heterogeneity. MicroRNAs have important biological functions and play critical roles in …

miR-148a-3p suppresses the progression of acute myeloid leukemia via targeting cyclin-dependent kinase 6 (CDK6)

H Zhou, X Jia, F Yang, P Shi - Bioengineered, 2021 - Taylor & Francis
To study the regulation of miR-148a-3p on CDK6 and its mechanism in the progress of acute
myeloid leukemia (AML), differential miRNAs were analyzed by bioinformatics, and the miR …